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What the FDA labels say about taking them together

Raloxifene and warfarin

Raloxifene's FDA label of April 14, 2026 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name raloxifene. The raloxifene label: “Reduces the absorption and enterohepatic cycling of raloxifene. Warfarin: Monitor prothrombin time when starting or stopping EVISTA.”

Check it at the source: the raloxifene FDA label on DailyMed (effective April 14, 2026, Amneal Pharmaceuticals LLC); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the raloxifene label say about warfarin?

Raloxifene label, drug interactions

Reduces the absorption and enterohepatic cycling of raloxifene. (7.1, 12.3) Warfarin: Monitor prothrombin time when starting or stopping raloxifene hydrochloride.

Source: FDA drug label (Evista, NDA020815), Eli Lilly and Company, effective February 11, 2026 (SPL set fcaaa6dc-74e8-4fb8-800c-5574bf0f8de9), via openFDA

Source: FDA drug label (Raloxifene Hydrochloride), Amneal Pharmaceuticals LLC, effective April 14, 2026 (SPL set 3798c70b-a4b0-4811-9788-e4c9cff47ebe), via openFDA; the full label on DailyMed

What does the warfarin label say about raloxifene?

Warfarin's label (effective May 29, 2026) does not name raloxifene in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

17Raloxifene generic labelers
19Warfarin generic labelers
RaloxifeneWarfarin
Labeled forOsteoporosis, Breast cancerBlood clots (DVT and PE), Atrial fibrillation
Boxed warningYesYes
Pharmacy cost (NADAC)$0.223 per tablet 60 mg tablet$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?