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What the FDA labels say about taking them together

Diazoxide and raloxifene

Raloxifene's FDA label of April 14, 2026 names diazoxide in its drug interactions section; the diazoxide labels PlainMeds reads (2) do not name raloxifene.

Check it at the source: the diazoxide FDA label on DailyMed (effective March 26, 2025, Soleno Therapeutics, Inc.); the raloxifene FDA label on DailyMed (effective April 14, 2026, Amneal Pharmaceuticals LLC).

What does the diazoxide label say about raloxifene?

Diazoxide's label (effective March 26, 2025) and its 1 other brand-application label do not name raloxifene in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (VYKAT XR), Soleno Therapeutics, Inc., effective March 26, 2025 (SPL set 0e745e85-9512-e360-e063-6394a90aebf1), via openFDA; the full label on DailyMed

What does the raloxifene label say about diazoxide?

Raloxifene label, drug interactions

Raloxifene hydrochloride should be used with caution with certain other highly protein-bound drugs such as diazepam, diazoxide, and lidocaine.

Source: FDA drug label (Evista, NDA020815), Eli Lilly and Company, effective February 11, 2026 (SPL set fcaaa6dc-74e8-4fb8-800c-5574bf0f8de9), via openFDA

Source: FDA drug label (Raloxifene Hydrochloride), Amneal Pharmaceuticals LLC, effective April 14, 2026 (SPL set 3798c70b-a4b0-4811-9788-e4c9cff47ebe), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Diazoxide generic labelers
17Raloxifene generic labelers
DiazoxideRaloxifene
Labeled forn/aOsteoporosis, Breast cancer
Boxed warningNoYes
Pharmacy cost (NADAC)$7.38 per mL 50 mg/mL oral suspension$0.223 per tablet 60 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?