colestipol vs furosemide
Side-by-side comparison of colestipol and furosemide. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride.
Recommendation: Do not take these two medicines at the exact same time. Ask your doctor about spacing the doses out by at least one hour.
Colestid
Lasix
Colestipol is a drug that helps lower cholesterol levels in your blood. It works by binding to bile acids in your intestine, which helps your body get rid of cholesterol.
Furosemide is a water pill (diuretic). It helps your body get rid of extra water and salt.
Colestipol is used along with a healthy diet to lower high cholesterol levels, specifically LDL-C ('bad' cholesterol). It is for people who haven't been able to lower their cholesterol enough with diet alone. Lowering cholesterol can help prevent heart disease and stroke.
This medicine treats swelling (edema) from heart failure, liver problems, or kidney disease. It can also treat high blood pressure. Furosemide is helpful when you need a stronger diuretic.
Colestipol is a bile acid sequestrant. It binds to bile acids in your intestines. This helps your body get rid of cholesterol, which lowers the amount of cholesterol in your blood.
Furosemide works in your kidneys. It helps your kidneys remove more salt and water from your blood. This lowers the amount of fluid in your body and lowers blood pressure.
- • Constipation
- • Abdominal discomfort (pain and cramping)
- • Intestinal gas (bloating and flatulence)
- • Indigestion and heartburn
- • Diarrhea and loose stools
- • Dizziness
- • Headache
- • Blurred vision
- • Nausea
- • Vomiting
- Diarrhea 358
- Feeling sick to your stomach 221
- Feeling tired 210
- Headache 136
- Throwing up 125
- Difficulty breathing 29,099
- Tiredness 20,389
- Diarrhea 19,940
- Feeling sick to your stomach 18,682
- Sudden kidney damage 18,530
None
Furosemide can cause you to lose too much fluid and electrolytes. This can lead to dehydration, low blood pressure, and kidney problems. Your doctor should check your blood regularly while you are taking this medicine.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if colestipol can harm an unborn baby. Talk to your doctor about the risks and benefits of taking this medicine while pregnant or breastfeeding.
Tell your doctor if you are pregnant or plan to become pregnant. Furosemide may not be safe during pregnancy. Talk to your doctor about the risks and benefits of taking this medicine while breastfeeding.
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How to Read This colestipol vs furosemide Comparison
colestipol is classified in the Bile Acid Sequestrant drug class, while furosemide sits within the Loop Diuretic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, colestipol has 1,050 submissions while furosemide has 106,640. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to colestipol can trap furosemide in the gut, which stops the medicine from getting into your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between colestipol and furosemide - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.