Clarithromycin · more major-labeled pairs than Rosiglitazone
SPL labels Clarithromycin + Rosiglitazone as major; Clarithromycin 16 / Rosiglitazone 1 in that band.
Mechanism on file: Clarithromycin slows down the process your body uses to get rid of rosiglitazone, which can cause the drug to build up in your system.
FDA SPL severity: Major
Clarithromycin + Rosiglitazone · SPL mechanism field
Clarithromycin slows down the process your body uses to get rid of rosiglitazone, which can cause the drug to build up in your system.
Major band excerpt · Clarithromycin with Rosiglitazone
Gastroprokinetic Agents: Cisapride Contraindicated Cisapride: [See Contraindications ( 4.2 )] Lipid-lowering agents: Lomitapide Lovastatin Simvastatin Contraindicated Lomitapide, Lovastatin, Simvastatin: Clarithromycin may increase the exposure of these drugs by inhibition of CYP3A metabolism, thereby increasing the risk of toxicities from these drugs [see Contraindications ( 4.5 ) and Warnings and Precautions ( 5.4 )] Atorvastatin, Pravastatin, Fluvastatin: [See Warnings and Precautions ( 5.4 )] Atorvastatin Pravastatin Use With Caution Fluvastatin No Dose Adjustment Hypoglycemic Agents:...
Clarithromycin · 16 major-labeled pairs (vs Rosiglitazone's 1)
- Atorvastatin major
- Colchicine major
- Cyclosporine major
- Dronedarone major
Rosiglitazone · 1 major + 12 total pairs
- Amiloride minor
- Cimetidine minor
- Digoxin minor
- Gemfibrozil minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.