Amiloride · larger labeled portfolio than Rosiglitazone
SPL labels Rosiglitazone + Amiloride as minor; Rosiglitazone 11 / Amiloride 11 in that band.
Mechanism on file: These drugs are both removed by the kidneys using the same transport system, which could lead to higher levels of the medicine in your blood.
FDA SPL severity: Minor
Rosiglitazone + Amiloride · SPL mechanism field
These drugs are both removed by the kidneys using the same transport system, which could lead to higher levels of the medicine in your blood.
Minor band excerpt · Rosiglitazone with Amiloride
[See Clinical Pharmacology (12.4).] 7.2 Cationic Drugs Although drug interactions for metformin with cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, and vancomycin) remain theoretical (except for cimetidine), careful patient monitoring and dose adjustment of AVANDAMET and/or the interfering drug is recommended in patients who are taking cationic medications that are excreted via the proximal renal tubular secretory system.
Rosiglitazone · 11 minor + 12 total pairs
- Cimetidine minor
- Digoxin minor
- Gemfibrozil minor
- Leflunomide minor
Amiloride · 19 SPL pairs (broader portfolio than Rosiglitazone)
- Amlodipine/Valsartan minor
- Enalapril minor
- Hydrochlorothiazide minor
- Hydrochlorothiazide/Lisinopril minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.