Clarithromycin · more major-labeled pairs than Atorvastatin
SPL labels Clarithromycin + Atorvastatin as major; Clarithromycin 16 / Atorvastatin 3 in that band.
Mechanism on file: Clarithromycin slows down how fast your body processes atorvastatin, which can cause the statin levels to rise too high.
FDA SPL severity: Major
Clarithromycin + Atorvastatin · SPL mechanism field
Clarithromycin slows down how fast your body processes atorvastatin, which can cause the statin levels to rise too high.
Major band excerpt · Clarithromycin with Atorvastatin
Intervention: In patients taking clarithromycin or itraconazole, do not exceed atorvastatin 20 mg [see Dosage and Administration (2.5) ]. Examples: Erythromycin, clarithromycin, itraconazole, ketoconazole, posaconazole, and voriconazole.
Clarithromycin · 16 major-labeled pairs (vs Atorvastatin's 3)
- Colchicine major
- Cyclosporine major
- Dronedarone major
- Fluconazole major
Atorvastatin · 3 major + 36 total pairs
- Darunavir major
- Itraconazole major
- Amiodarone minor
- Bazedoxifene/Conjugated Estrogens minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.