Digoxin · more major-labeled pairs than Rosiglitazone
SPL labels Rosiglitazone + Digoxin as minor; Rosiglitazone 11 / Digoxin 105 in that band.
Mechanism on file: Both drugs are processed by the same part of the kidney, which might interfere with how quickly the body gets rid of them.
FDA SPL severity: Minor
Rosiglitazone + Digoxin · SPL mechanism field
Both drugs are processed by the same part of the kidney, which might interfere with how quickly the body gets rid of them.
Minor band excerpt · Rosiglitazone with Digoxin
[See Clinical Pharmacology (12.4).] 7.2 Cationic Drugs Although drug interactions for metformin with cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, and vancomycin) remain theoretical (except for cimetidine), careful patient monitoring and dose adjustment of AVANDAMET and/or the interfering drug is recommended in patients who are taking cationic medications that are excreted via the proximal renal tubular secretory system.
Rosiglitazone · 11 minor + 12 total pairs
- Amiloride minor
- Cimetidine minor
- Gemfibrozil minor
- Leflunomide minor
Digoxin · 2 major-labeled pairs (vs Rosiglitazone's 1)
- Acarbose minor
- Albuterol minor
- Amiodarone minor
- Atorvastatin minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
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