What the FDA labels say about taking them together
Clarithromycin and cyclosporine
Clarithromycin's FDA label of April 9, 2026 names cyclosporine in its drug interactions section, and cyclosporine's label names clarithromycin too.
Check it at the source: the clarithromycin FDA label on DailyMed (effective April 9, 2026, Solaris Pharma Corporation); the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation).
What does the clarithromycin label say about cyclosporine?
Clarithromycin label, drug interactionsCyclosporine Use With Caution Cyclosporine: There have been spontaneous or published reports of CYP3A based interactions of clarithromycin with cyclosporine.
Source: FDA drug label (Clarithromycin), Solaris Pharma Corporation, effective April 9, 2026 (SPL set 4d42821d-ce7a-7d64-e063-6294a90a0875), via openFDA; the full label on DailyMed
What does the cyclosporine label say about clarithromycin?
Cyclosporine label, drug interactionsnicardipine; itraconazole; clarithromycin; Amiodarone
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clarithromycin | Cyclosporine | |
|---|---|---|
| Labeled for | Bacterial infections, Acid reflux and ulcers | Organ transplant rejection, Rheumatoid arthritis |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.466 per tablet 500 mg tablet | $1.04 per unit 0.05% eye emulsion |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once