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clarithromycin vs rosiglitazone

Side-by-side comparison of clarithromycin and rosiglitazone. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

major Known Drug Interaction

Gastroprokinetic Agents: Cisapride Contraindicated Cisapride: [See Contraindications ( 4.2 )] Lipid-lowering agents: Lomitapide Lovastatin Simvastatin Contraindicated Lomitapide, Lovastatin, Simvastatin: Clarithromycin may increase the exposure of these drugs by inhibition of CYP3A metabolism, thereby increasing the risk of toxicities from these drugs [see Contraindications ( 4.5 ) and Warnings and Precautions ( 5.4 )] Atorvastatin, Pravastatin, Fluvastatin: [See Warnings and Precautions ( 5.4 )] Atorvastatin Pravastatin Use With Caution Fluvastatin No Dose Adjustment Hypoglycemic Agents:...

Recommendation: Your doctor may need to monitor your blood sugar levels more closely and adjust your medication if needed.

Drug Class
clarithromycin Macrolide Antibiotic
rosiglitazone Thiazolidinedione
Type
clarithromycin Prescription
rosiglitazone Prescription
Summary
clarithromycin

Clarithromycin is an antibiotic that fights bacterial infections. It belongs to a class of drugs called macrolides.

rosiglitazone

No summary available.

What It Treats
clarithromycin

Clarithromycin treats mild to moderate infections caused by certain bacteria. It can treat bronchitis, sinus infections, pneumonia, and throat/tonsil infections. It also treats skin infections, ear infections in children, certain mycobacterial infections, and H. pylori infections that cause ulcers.

rosiglitazone

Information not available.

How It Works
clarithromycin

Clarithromycin works by stopping the growth of bacteria. It prevents bacteria from making proteins they need to survive. This helps your body fight off the infection.

rosiglitazone

Information not available.

Common Side Effects
clarithromycin
  • Abdominal pain
  • Diarrhea
  • Nausea
  • Vomiting
  • Taste changes
rosiglitazone
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Upset stomach
FAERS Reports
clarithromycin
  • Drug Interaction 2,906
  • Nausea 2,214
  • Dyspnoea 1,959
  • Diarrhoea 1,937
  • Malaise 1,650
rosiglitazone

No adverse event reports.

Serious Warnings
clarithromycin

Clarithromycin can cause severe allergic reactions. Stop taking it and get medical help right away if you have signs of a reaction. This medicine can also cause heart rhythm problems (QT prolongation) and liver problems. Tell your doctor if you have heart or liver issues. Clarithromycin may increase the risk of death in patients with coronary artery disease.

rosiglitazone

No specific warnings noted.

Pregnancy
clarithromycin

Clarithromycin is not recommended during pregnancy unless there are no other options. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if clarithromycin passes into breast milk, so talk to your doctor before breastfeeding.

rosiglitazone

No pregnancy information available.

Also Compare, Nearby Drugs

How to Read This clarithromycin vs rosiglitazone Comparison

clarithromycin is classified in the Macrolide Antibiotic drug class, while rosiglitazone sits within the Thiazolidinedione class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, clarithromycin has 10,666 submissions while rosiglitazone has 0. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known major interaction flagged in FDA labeling, attributed to clarithromycin slows down the process your body uses to get rid of rosiglitazone, which can cause the drug to build up in your system.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between clarithromycin and rosiglitazone - always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.