Skip to main content

What the FDA labels say about taking them together

Cidofovir and gentamicin

Cidofovir's FDA label of October 25, 2023 names gentamicin in its drug interactions section; the gentamicin label PlainMeds reads does not name cidofovir. The cidofovir label: “Nephrotoxic agents Concomitant administration of cidofovir injection and agents with nephrotoxic potential [e.g., intravenous aminoglycosides, amphotericin B, foscarnet, intravenous pentamidine, vancomycin, and …”

Check it at the source: the cidofovir FDA label on DailyMed (effective October 25, 2023, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.); the gentamicin FDA label on DailyMed (effective July 22, 2024, Bausch & Lomb Incorporated).

What does the cidofovir label say about gentamicin?

Cidofovir label, drug interactions

Nephrotoxic agents Concomitant administration of cidofovir injection and agents with nephrotoxic potential [e.g., intravenous aminoglycosides (e.g., tobramycin, gentamicin, and amikacin), amphotericin B, foscarnet, intravenous pentamidine, vancomycin, and nonsteroidal anti-inflammatory agents] is contraindicated.

Cidofovir label, warnings

The safety of cidofovir injection has not been evaluated in patients receiving other known potentially nephrotoxic agents, such as intravenous aminoglycosides (e.g., tobramycin, gentamicin, and amikacin), amphotericin B, foscarnet, intravenous pentamidine, vancomycin, and non-steroidal anti-inflammatory agents (see DOSAGE AND ADMINISTRATION ).

Source: FDA drug label (CIDOFOVIR DIHYDRATE), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective October 25, 2023 (SPL set 44966a7e-d777-40fb-956f-d0f31f737848), via openFDA; the full label on DailyMed

What does the gentamicin label say about cidofovir?

Gentamicin's label (effective July 22, 2024) does not name cidofovir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Gentamicin Sulfate), Bausch & Lomb Incorporated, effective July 22, 2024 (SPL set 41d01350-5c4b-42fc-be5f-986ceec02bd3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Cidofovir generic labelers
24Gentamicin generic labelers
CidofovirGentamicin
Labeled forn/aBacterial infections
Boxed warningYesNo
Pharmacy cost (NADAC)n/a$1.30 per mL 80 mg/2 mL vial
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?