What the FDA labels say about taking them together
Cidofovir and vancomycin
Cidofovir's FDA label of October 25, 2023 names vancomycin in its drug interactions section; the vancomycin labels PlainMeds reads (4) do not name cidofovir. The cidofovir label: “… intravenous aminoglycosides, amphotericin B, foscarnet, intravenous pentamidine, vancomycin, and nonsteroidal anti-inflammatory agents] is contraindicated.”
Check it at the source: the cidofovir FDA label on DailyMed (effective October 25, 2023, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.); the vancomycin FDA label on DailyMed (effective June 7, 2024, Mylan Institutional LLC).
What does the cidofovir label say about vancomycin?
Cidofovir label, drug interactionsNephrotoxic agents Concomitant administration of cidofovir injection and agents with nephrotoxic potential [e.g., intravenous aminoglycosides (e.g., tobramycin, gentamicin, and amikacin), amphotericin B, foscarnet, intravenous pentamidine, vancomycin, and nonsteroidal anti-inflammatory agents] is contraindicated.
Cidofovir label, warningsThe safety of cidofovir injection has not been evaluated in patients receiving other known potentially nephrotoxic agents, such as intravenous aminoglycosides (e.g., tobramycin, gentamicin, and amikacin), amphotericin B, foscarnet, intravenous pentamidine, vancomycin, and non-steroidal anti-inflammatory agents (see DOSAGE AND ADMINISTRATION ).
Source: FDA drug label (CIDOFOVIR DIHYDRATE), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective October 25, 2023 (SPL set 44966a7e-d777-40fb-956f-d0f31f737848), via openFDA; the full label on DailyMed
What does the vancomycin label say about cidofovir?
Vancomycin's label (effective June 7, 2024) and its 3 other brand-application labels do not name cidofovir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Vancomycin Hydrochloride), Mylan Institutional LLC, effective June 7, 2024 (SPL set caf22ccb-df75-45ea-a1d0-ccb2d37272fb), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cidofovir | Vancomycin | |
|---|---|---|
| Labeled for | n/a | Bacterial infections, Diarrhea |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $1.33 per capsule 125 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once