Atomoxetine and Warfarin Interaction
Drug interaction information between Atomoxetine and Warfarin.
Atomoxetine and Warfarin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Atomoxetine and Warfarin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Atomoxetine does not interfere with how warfarin attaches to proteins in the blood, so it should not change how well the blood thinner works.
FDA Label Information
Atomoxetine did not affect the binding of warfarin, acetylsalicylic acid, phenytoin, or diazepam to human albumin.
Atomoxetine Also Interacts With
- Albuterol moderate
- Omeprazole minor
- Fluoxetine minor
- Methylphenidate minor
- Diazepam minor
Warfarin Also Interacts With
- Fluoxetine major
- Tamoxifen major
- Ibuprofen moderate
- Aspirin moderate
- Diclofenac moderate
Frequently Asked Questions
What SPL severity band is on file for Atomoxetine + Warfarin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Warfarin has 163 labeled pairs on file vs Atomoxetine's 15. In the minor band specifically: Atomoxetine has 14 (also Omeprazole, Fluoxetine, Methylphenidate, Diazepam); Warfarin has 133 (also Atorvastatin, Amlodipine, Omeprazole, Famotidine).
What mechanism field is on file for Atomoxetine and Warfarin?
Atomoxetine does not interfere with how warfarin attaches to proteins in the blood, so it should not change how well the blood thinner works.
Warfarin carries more major-labeled pairs than Atomoxetine
SPL source-record counts only. This page's band is minor · classes on file: Atomoxetine (Selective Norepinephrine Reuptake Inhibitor); Warfarin (Vitamin K Antagonist (Anticoagulant)).
Warfarin has 2 major-labeled pairs vs Atomoxetine's 0. This page itself is in the minor band, not the major band.
0 major · 1 moderate · 14 minor · 15 total
- Other minor peers for Atomoxetine
- Omeprazole
- Fluoxetine
- Methylphenidate
- Diazepam
2 major · 28 moderate · 133 minor · 163 total
- Other minor peers for Warfarin
- Atorvastatin
- Amlodipine
- Omeprazole
- Famotidine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.