Atomoxetine and Albuterol Interaction

Drug interaction information between Atomoxetine and Albuterol.

Atomoxetine and Albuterol have a documented moderate interaction in FDA labeling.

FDA drug labeling documents a moderate-severity interaction between Atomoxetine and Albuterol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Atomoxetine

Selective Norepinephrine Reuptake Inhibitor

Drug B

Albuterol

Short-Acting Beta-2 Agonist

How They Interact

Atomoxetine can make the effects of albuterol on your heart and blood vessels much stronger. This can cause your heart to beat faster and your blood pressure to rise.

FDA Label Information

( 7.3 ) • Albuterol (or other beta 2 agonists) - Action of albuterol on cardiovascular system can be potentiated. 7.4 Albuterol Atomoxetine should be administered with caution to patients being treated with systemically-administered (oral or intravenous) albuterol (or other beta 2 agonists) because the action of albuterol on the cardiovascular system can be potentiated resulting in increases in heart rate and blood pressure. Albuterol (600 mcg iv over 2 hours) induced increases in heart rate and blood pressure.

Frequently Asked Questions

What SPL severity band is on file for Atomoxetine + Albuterol?

Compiled FDA labeling labels this pair moderate. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Albuterol has 16 labeled pairs on file vs Atomoxetine's 15. In the moderate band specifically: Atomoxetine has 1; Albuterol has 2 (also Albuterol/Ipratropium).

What mechanism field is on file for Atomoxetine and Albuterol?

Atomoxetine can make the effects of albuterol on your heart and blood vessels much stronger. This can cause your heart to beat faster and your blood pressure to rise.

Albuterol carries more major-labeled pairs than Atomoxetine

SPL source-record counts only. This page's band is moderate · classes on file: Atomoxetine (Selective Norepinephrine Reuptake Inhibitor); Albuterol (Short-Acting Beta-2 Agonist).

Albuterol has 1 major-labeled pair vs Atomoxetine's 0. This page itself is in the moderate band, not the major band.

Atomoxetine

0 major · 1 moderate · 14 minor · 15 total

Atomoxetine has no other moderate-band peer in this dataset besides Albuterol.

Albuterol

1 major · 2 moderate · 13 minor · 16 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.