Atomoxetine and Albuterol Interaction
Drug interaction information between Atomoxetine and Albuterol.
Atomoxetine and Albuterol have a documented moderate interaction in FDA labeling.
FDA drug labeling documents a moderate-severity interaction between Atomoxetine and Albuterol. Major interactions are generally avoided, moderate ones may need monitoring or a dose adjustment, and minor ones are usually low-risk. This page shows the documented mechanism and guidance. Label-documented interactions are not a complete safety review, so always confirm your own medications with a pharmacist or doctor. Educational information, not medical advice.
How They Interact
Atomoxetine can make the effects of albuterol on your heart and blood vessels much stronger. This can cause your heart to beat faster and your blood pressure to rise.
What To Do
Use these medications together with caution and under a doctor's supervision. Your provider should regularly check your heart rate and blood pressure.
FDA Label Information
( 7.3 ) • Albuterol (or other beta 2 agonists) - Action of albuterol on cardiovascular system can be potentiated. 7.4 Albuterol Atomoxetine should be administered with caution to patients being treated with systemically-administered (oral or intravenous) albuterol (or other beta 2 agonists) because the action of albuterol on the cardiovascular system can be potentiated resulting in increases in heart rate and blood pressure. Albuterol (600 mcg iv over 2 hours) induced increases in heart rate and blood pressure.
Atomoxetine Also Interacts With
- Omeprazole minor
- Fluoxetine minor
- Methylphenidate minor
- Warfarin minor
- Diazepam minor
Albuterol Also Interacts With
- Theophylline major
- Albuterol/Ipratropium moderate
- Digoxin minor
- Glimepiride minor
- Insulin Aspart minor
Frequently Asked Questions
Can I take Atomoxetine and Albuterol together?
This is a moderate interaction. Use these medications together with caution and under a doctor's supervision. Your provider should regularly check your heart rate and blood pressure.
How serious is the interaction between Atomoxetine and Albuterol?
This interaction is classified as "moderate" severity by the FDA. Moderate interactions may worsen your condition or change how your medications work.
Why do Atomoxetine and Albuterol interact?
Atomoxetine can make the effects of albuterol on your heart and blood vessels much stronger. This can cause your heart to beat faster and your blood pressure to rise.
Understanding the Atomoxetine and Albuterol Interaction
FDA-approved prescribing information for these two drugs flags their combination as a moderate-severity interaction. Atomoxetine belongs to the Selective Norepinephrine Reuptake Inhibitor class and Albuterol belongs to the Short-Acting Beta-2 Agonist class - two categories that can collide when co-prescribed. The mechanism described in FDA labeling is: Atomoxetine can make the effects of albuterol on your heart and blood vessels much stronger. Severity tiers matter: major flags generally advise avoidance, moderate flags often require monitoring or dose adjustment, and minor flags may only call for awareness.
Context around a specific patient determines real-world impact. Atomoxetine has 15 total documented interactions on file in this dataset, and Albuterol has 16. Each additional medication compounds the interaction surface, which is why pharmacists run full-profile checks rather than evaluating one pair at a time. FDA-derived guidance for this pair is: Use these medications together with caution and under a doctor's supervision. Timing of doses, renal and hepatic function, age, and other concurrent prescriptions all shape whether a labeled interaction matters clinically.
An interaction flag is not a verdict. A large share of labeled interactions are managed routinely in clinical practice, the fix may be as simple as spacing doses or adding a monitoring test. Others require the prescriber to choose a different medication entirely. This page surfaces FDA-sourced labeling and openFDA data for educational purposes only; it is not medical advice and cannot account for your full clinical picture. Never start, stop, or adjust either Atomoxetine or Albuterol based on a web page, speak with your prescriber or pharmacist before making any change.
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. Always consult your healthcare provider about drug interactions.
Read our methodology - how this data is sourced, computed, and verified.