Atomoxetine and Diazepam Interaction

Drug interaction information between Atomoxetine and Diazepam.

Atomoxetine and Diazepam have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Atomoxetine and Diazepam. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Atomoxetine

Selective Norepinephrine Reuptake Inhibitor

Drug B

Diazepam

Benzodiazepine

How They Interact

Atomoxetine does not change how diazepam binds to proteins in your blood, meaning it does not affect the amount of active medicine in your system.

FDA Label Information

Atomoxetine did not affect the binding of warfarin, acetylsalicylic acid, phenytoin, or diazepam to human albumin.

Diazepam Also Interacts With

View all Diazepam interactions →

Frequently Asked Questions

What SPL severity band is on file for Atomoxetine + Diazepam?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Diazepam has 26 labeled pairs on file vs Atomoxetine's 15. In the minor band specifically: Atomoxetine has 14 (also Omeprazole, Fluoxetine, Methylphenidate, Warfarin); Diazepam has 22 (also Omeprazole, Ketoconazole, Fluvoxamine, Cimetidine).

What mechanism field is on file for Atomoxetine and Diazepam?

Atomoxetine does not change how diazepam binds to proteins in your blood, meaning it does not affect the amount of active medicine in your system.

Diazepam's labeled portfolio outnumbers Atomoxetine

SPL source-record counts only. This page's band is minor · classes on file: Atomoxetine (Selective Norepinephrine Reuptake Inhibitor); Diazepam (Benzodiazepine).

Atomoxetine

0 major · 1 moderate · 14 minor · 15 total

Diazepam

0 major · 4 moderate · 22 minor · 26 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.