Albendazole and Dexamethasone Interaction

Drug interaction information between Albendazole and Dexamethasone.

Albendazole and Dexamethasone have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Albendazole and Dexamethasone. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Albendazole

Antiparasitic (Benzimidazole)

Drug B

Dexamethasone

Corticosteroid

How They Interact

Dexamethasone increases the amount of the active form of albendazole that stays in your bloodstream.

FDA Label Information

7 DRUG INTERACTIONS Dexamethasone: Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when dexamethasone was coadministered with each dose of albendazole. ( 5.5 , 7.4 ) 7.1 Dexamethasone Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was co-administered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.

Frequently Asked Questions

What SPL severity band is on file for Albendazole + Dexamethasone?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Dexamethasone has 21 labeled pairs on file vs Albendazole's 5. In the minor band specifically: Albendazole has 5 (also Theophylline, Cimetidine, Carbamazepine, Phenytoin); Dexamethasone has 18 (also Warfarin, Cyclosporine, Hydrocortisone, Erythromycin).

What mechanism field is on file for Albendazole and Dexamethasone?

Dexamethasone increases the amount of the active form of albendazole that stays in your bloodstream.

Dexamethasone's labeled portfolio outnumbers Albendazole

SPL source-record counts only. This page's band is minor · classes on file: Albendazole (Antiparasitic (Benzimidazole)); Dexamethasone (Corticosteroid).

Albendazole

0 major · 0 moderate · 5 minor · 5 total

Dexamethasone

0 major · 3 moderate · 18 minor · 21 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.