Albendazole and Theophylline Interaction
Drug interaction information between Albendazole and Theophylline.
Albendazole and Theophylline have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Albendazole and Theophylline. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Albendazole can make your liver work faster to clear theophylline from your body, which could make the theophylline less effective.
FDA Label Information
( 7.3 ) Theophylline: Albendazole induces cytochrome P450 1A in human hepatoma cells; therefore, it is recommended that plasma concentrations of theophylline be monitored during and after treatment. 7.4 Theophylline Following a single dose of albendazole (400 mg), the pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged. Albendazole induces cytochrome P450 1A in human hepatoma cells; therefore, it is recommended that plasma concentrations of theophylline be monitored during and after treatment.
Albendazole Also Interacts With
- Cimetidine minor
- Dexamethasone minor
- Carbamazepine minor
- Phenytoin minor
Theophylline Also Interacts With
- Metoprolol major
- Albuterol major
- Omeprazole major
- Amoxicillin major
- Famotidine major
Frequently Asked Questions
What SPL severity band is on file for Albendazole + Theophylline?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Theophylline has 86 labeled pairs on file vs Albendazole's 5. In the minor band specifically: Albendazole has 5 (also Cimetidine, Dexamethasone, Carbamazepine, Phenytoin); Theophylline has 54 (also Propranolol, Methotrexate, Diazepam, Lithium).
What mechanism field is on file for Albendazole and Theophylline?
Albendazole can make your liver work faster to clear theophylline from your body, which could make the theophylline less effective.
Theophylline carries more major-labeled pairs than Albendazole
SPL source-record counts only. This page's band is minor · classes on file: Albendazole (Antiparasitic (Benzimidazole)); Theophylline (Methylxanthine Bronchodilator).
Theophylline has 27 major-labeled pairs vs Albendazole's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 5 minor · 5 total
- Other minor peers for Albendazole
- Cimetidine
- Dexamethasone
- Carbamazepine
- Phenytoin
27 major · 5 moderate · 54 minor · 86 total
- Other minor peers for Theophylline
- Propranolol
- Methotrexate
- Diazepam
- Lithium
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.