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albendazole

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Brand names: Albenza

Antiparasitic (Benzimidazole) Rx

Albendazole is a medicine that fights parasites. It is used to treat infections caused by tapeworms.

Drug Pricing (NADAC)

Generic Price

$7.16/unit

Generic Available

Yes (5 manufacturers)

Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →

What it does

Albendazole treats infections caused by tapeworms.

Common side effects

Abnormal liver function tests, Abdominal pain, Nausea

Key warnings

Albendazole can cause bone marrow suppression, which can be fatal.

How It Works

Albendazole stops the tapeworms from growing and multiplying. It does this by blocking the worm's ability to use sugar (glucose). This eventually kills the parasite.

How to Take It

Take albendazole with food. If you weigh 60 kg (132 lbs) or more, the usual dose is 400 mg twice a day. If you weigh less than 60 kg, the dose is 15 mg per kg of body weight per day, divided into two doses. Do not take more than 800 mg per day. You can crush or chew the tablets and swallow them with water.

Pregnancy & Breastfeeding

Albendazole can harm an unborn baby. Women who can get pregnant should use effective birth control while taking albendazole and for one month after stopping the medicine. If you become pregnant while taking albendazole, tell your doctor right away.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Storage

Store albendazole at room temperature, between 68° to 77°F (20° to 25°C).

Side Effects (from patient reports)

Based on 2,206 FDA adverse event reports.

The medicine did not work
365
Using the medicine for a condition it's not approved for
284
Fever
236
Using the product for a condition it's not approved for
224
Headache
222
Condition got worse
213
Tiredness
167
Weight loss
166
Rash
165
Pain
164

FDA Adverse Event Report Analysis

Detailed analysis of 1,829 reports from the FDA Adverse Event Reporting System (FAERS). Reports span 2004–2025.

Total Reports

1,829

Death-Related Reports

302

Hospitalization Reports

658

Top Indication

Product Used For Unknown Indication

Gender Distribution

Female 758 (47%)
Male 860 (53%)

Age Distribution

0–17 226
18–44 466
45–64 518
65–74 143
75+ 68

Most Reported Adverse Reactions (FAERS)

# Reaction Reports
1 DRUG INEFFECTIVE 365
2 OFF LABEL USE 284
3 PYREXIA 236
4 PRODUCT USE IN UNAPPROVED INDICATION 224
5 HEADACHE 222
6 CONDITION AGGRAVATED 213
7 FATIGUE 167
8 WEIGHT DECREASED 166
9 RASH 165
10 PAIN 164
11 SOMNOLENCE 159
12 HAEMATOCHEZIA 157
13 RECTAL HAEMORRHAGE 149
14 COLITIS ULCERATIVE 148
15 STRESS 148

Reactions in Death Reports

DRUG INEFFECTIVE 69
DEATH 64
STRONGYLOIDIASIS 44
PYREXIA 33
SEPSIS 28
RESPIRATORY FAILURE 26
SEPTIC SHOCK 25
DIARRHOEA 24
OFF LABEL USE 24
VOMITING 20

Reactions in Hospitalization Reports

DRUG INEFFECTIVE 92
PYREXIA 90
VOMITING 75
HEADACHE 62
ASTHENIA 60
OFF LABEL USE 58
STRONGYLOIDIASIS 54
CONDITION AGGRAVATED 52
DIARRHOEA 47
SOMNOLENCE 33

Source: FDA FAERS (Adverse Event Reporting System) FDA FAERS (Adverse Event Reporting System) Reports are voluntary and do not establish causation

Serious Warnings

Albendazole can cause bone marrow suppression, which can be fatal. Your doctor will check your blood counts before and during treatment. If your blood counts drop too low, you may need to stop taking albendazole. Albendazole can also harm an unborn baby, so women who can get pregnant should use birth control while taking it. If you are being treated for neurocysticercosis, you may experience seizures or other neurological problems. Your doctor may give you steroids and anti-seizure medicine to prevent these problems.

Known Drug Interactions

( 7.3 ) Theophylline: Albendazole induces cytochrome P450 1A in human hepatoma cells; therefore, it is recommended that plasma concentrations of theophylline be monitored during and after treatment. 7.4 Theophylline Following a single dose of albendazole (400 mg), the pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged. Albendazole induces cytochrome P450 1A in human hepatoma cells; therefore, it is recommended that plasma concentrations of theophylline be monitored during and after treatment.

Mechanism: Albendazole can make your liver work faster to clear theophylline from your body, which could make the theophylline less effective.

What to do: Your doctor should check your theophylline blood levels while you are taking this medicine and after you stop.

( 7.2 ) Cimetidine: Increased albendazole sulfoxide concentrations in bile and cystic fluid by about 2-fold in hydatid cyst patients. 7.3 Cimetidine Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12).

Mechanism: Cimetidine interferes with how the body breaks down albendazole, which causes the drug levels to rise in certain body fluids.

What to do: Your doctor may need to monitor you more closely for side effects since the drug levels in your body could increase.

7 DRUG INTERACTIONS Dexamethasone: Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when dexamethasone was coadministered with each dose of albendazole. ( 5.5 , 7.4 ) 7.1 Dexamethasone Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was co-administered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.

Mechanism: Dexamethasone increases the amount of the active form of albendazole that stays in your bloodstream.

What to do: Your healthcare provider may need to adjust your dose or watch for increased side effects when taking these together.

In addition, carbamazepine causes, or would be expected to cause, decreased levels of the following drugs, for which monitoring of concentrations or dosage adjustment may be necessary: acetaminophen, albendazole, alprazolam, aprepitant, buprenorphone, bupropion, citalopram, clonazepam, clozapine, corticosteroids (e.g., prednisolone, dexamethasone), cyclosporine, dicumarol, dihydropyridine calcium channel blockers (e.g., felodipine), doxycycline, ethosuximide, everolimus, haloperidol, imatinib, itraconazole, lamotrigine, levothyroxine, methadone, methsuximide, mianserin, midazolam, olanzapin...

Mechanism: Carbamazepine speeds up the way your body clears out albendazole. This means there may not be enough albendazole in your blood to treat your infection effectively.

What to do: Your doctor may need to increase your dose of albendazole or monitor you more closely to ensure the treatment is working. Follow up with your provider to check if the medication is still effective.

Phenytoin when given with the combination of fosamprenavir and ritonavir may increase the concentration of amprenavir Calcium channel blockers Nifedipine, nimodipine, nisoldipine, verapamil Other Albendazole (decreases active metabolite), chlorpropamide, clozapine, cyclosporine, digoxin, disopyramide, folic acid, methadone, mexiletine, praziquantel, quetiapine a The effect of phenytoin on phenobarbital, valproic acid and sodium valproate serum levels is unpredictable 7.3 Drug/Laboratory Test Interactions Care should be taken when using immunoanalytical methods to measure serum phenytoin con...

Mechanism: Phenytoin causes your body to process albendazole faster, which reduces the amount of the active medicine available to fight infection.

What to do: Your doctor may need to adjust your dose of albendazole or monitor your treatment more closely.

Common Questions

Can I take albendazole without food?
No, you should always take albendazole with food.
How long will I need to take albendazole?
The length of treatment depends on the type of infection you have. For hydatid disease, it is usually given in 28-day cycles with breaks in between. For neurocysticercosis, it can be taken for 8 to 30 days.
What should I do if I experience side effects?
Tell your doctor about any side effects you experience while taking albendazole.
Will albendazole interact with other medications I am taking?
Albendazole can interact with other medications, such as dexamethasone, praziquantel, cimetidine, and theophylline. Tell your doctor about all the medications you are taking.
Can I drink alcohol while taking albendazole?
Ask your doctor if it is safe to drink alcohol while taking albendazole.
What tests will I need while taking albendazole?
Your doctor will monitor your blood counts and liver enzymes before and during treatment.
Can I breastfeed while taking albendazole?
It is not known if albendazole passes into breast milk. Talk to your doctor before breastfeeding.
What if I can't swallow the tablet?
You can crush or chew the albendazole tablets and swallow them with a drink of water.
Is there a generic version of albendazole?
Yes, albendazole is available as a generic medication.
How soon will I feel better after starting albendazole?
It may take several days or weeks before you start to feel better. Continue taking albendazole as prescribed by your doctor.
What are the common side effects of albendazole?
The most commonly reported side effects of albendazole include Abnormal liver function tests, Abdominal pain, Nausea, Vomiting, Reversible hair loss. Based on 2,206 FDA adverse event reports. Always consult your healthcare provider about potential side effects.
Does albendazole interact with other medications?
Yes, albendazole has 5 known drug interactions. Notable interactions include theophylline, cimetidine, dexamethasone. Always inform your doctor about all medications you are taking.
What drug class is albendazole?
albendazole belongs to the Antiparasitic (Benzimidazole) drug class. It requires a prescription (Rx). Albendazole treats infections caused by tapeworms.
Is albendazole safe during pregnancy?
Albendazole can harm an unborn baby. Women who can get pregnant should use effective birth control while taking albendazole and for one month after stopping the medicine. Always consult your healthcare provider before using any medication during pregnancy or breastfeeding.

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What the FDA Data Shows for albendazole

The FDA label for albendazole (sold under brand names such as Albenza) classifies it as a prescription-only medication in the Antiparasitic (Benzimidazole) class. Albendazole treats infections caused by tapeworms. Official labeling lists 10 commonly reported side effects, including Abnormal liver function tests, Abdominal pain, Nausea.

Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 2,206 voluntary reports. The database also lists 5 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated minor severity. NADAC pricing from CMS shows a generic unit cost of $7.16.

Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.

Data Sources

Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).

FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.

Last updated: September 30, 2019

All federal data sources used on this page