FDA pharmacologic class
Phosphate Binder
13 medicines are in FDA's class of phosphate binders: sevelamer (Renvela), calcium gluconate, calcium chloride, lanthanum (Fosrenol), calcium acetate, iron sucrose (Venofer), ferric carboxymaltose (Injectafer), sodium ferric gluconate complex (Ferrlecit) and 5 more; 16 combination products also contain one. 14 of the 29 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is lactated ringers injection at $0.0038 per mL (NADAC).
Which medicines are phosphate binder?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Sevelamer | Renvela | 35 labelers | $0.214 per tablet 800 mg tablet | No | No current entry | 2 |
| Calcium carbonate and famotidine and magnesium hydroxide | Pepcid, Dual | 20 labelers | $0.258 per tablet Acid reducer complete tablet chewable | No | No current entry | 0 |
| Calcium chloride, dextrose, magnesium chloride, sodium chloride and sodium lactate | Delflex | none listed | n/a | No | A presentation being discontinued | 18 |
| Calcium gluconate | none listed | 8 labelers | n/a | No | No current entry | 2 |
| Calcium chloride | none listed | 13 labelers | n/a | No | A presentation being discontinued | 3 |
| Lanthanum | Fosrenol | 5 labelers | $3.15 per tablet 1,000 mg tablet chw | No | No current entry | 4 |
| Calcium acetate | none listed | 20 labelers | $0.170 per capsule 667 mg capsule | No | No current entry | 2 |
| Alanine, arginine and 19 other ingredients | Clinimix | none listed | n/a | No | No current entry | 5 |
| Calcium chloride, potassium chloride, sodium chloride and sodium lactate | none listed | 2 labelers | $0.0038 per mL Lactated ringers injection | No | No current entry | 5 |
| Iron sucrose | Venofer | 3 labelers | n/a | No | A presentation being discontinued | 4 |
| Calcium chloride, dextrose, potassium chloride, sodium chloride and sodium lactate | none listed | 1 labeler | n/a | No | No current entry | 0 |
| Ferric carboxymaltose | Injectafer | 1 labeler | n/a | Yes | No current entry | 1 |
| Calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate | Extraneal | none listed | n/a | No | No current entry | 0 |
| Calcium chloride and potassium chloride and sodium chloride | Ringers | none listed | n/a | No | No current entry | 0 |
| Sodium ferric gluconate complex | Ferrlecit | 1 labeler | n/a | No | No current entry | 1 |
| Calcium chloride, magnesium chloride and 4 other ingredients | Bss, Balanced | 1 labeler | n/a | No | No current entry | 0 |
| Calcium chloride, magnesium chloride, potassium chloride and sodium chloride | Plegisol, Cardioplegic | 2 labelers | n/a | No | A presentation being discontinued | 0 |
| Iron dextran | Infed | none listed | $18.89 per mL 100 mg/2 mL vial | Yes | No current entry | 0 |
| Alanine, arginine and 22 other ingredients | Perikabiven, Kabiven | none listed | n/a | No | No current entry | 1 |
| Tetraferric tricitrate decahydrate | Auryxia | none listed | $6.28 per tablet 210 mg tablet | No | No current entry | 0 |
| Anhydrous dextrose, calcium chloride and 5 other ingredients | Elliotts | none listed | n/a | No | No current entry | 0 |
| Calcium chloride, magnesium chloride and 3 other ingredients | Tpn | none listed | n/a | No | No current entry | 0 |
| Ferric citrate | none listed | 1 labeler | n/a | No | No current entry | 4 |
| Ferric maltol | Accrufer | none listed | $10.09 per capsule 30 mg capsule | No | No current entry | 0 |
| Ferric oxyhydroxide | Velphoro | none listed | $17.11 per tablet 500 mg chewable tablet | No | No current entry | 0 |
| Alanine, arginine and 18 other ingredients | Clinimix | none listed | n/a | No | No current entry | 0 |
| Anhydrous dextrose, calcium chloride and 5 other ingredients | Prismasol | none listed | n/a | No | No current entry | 0 |
| Anhydrous dextrose, calcium chloride and 4 other ingredients | Prismasol | none listed | n/a | No | No current entry | 0 |
| Calcium chloride, magnesium chloride and 4 other ingredients | Phoxillum | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price