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Prescription medicine

Tetraferric tricitrate decahydrate Brand names: Auryxia

Tetraferric tricitrate decahydrate (Auryxia) is a prescription medicine. No generic is listed; pharmacies paid $6.28 per ferric citrate 210 mg tablet in the October 7, 2026 NADAC survey.

  • No generic listed

Check it at the source: the tetraferric tricitrate decahydrate FDA label on DailyMed (effective December 4, 2024, Akebia Therapeutics, Inc.); every tetraferric tricitrate decahydrate label on DailyMed.

Highlights of the record

FDA label of December 4, 2024; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026; NADAC October 7, 2026

Used for

From the label: indications and usage

Auryxia is a phosphate binder indicated for the control of serum phosphorus levels in adult patients with chronic kidney disease on dialysis.

Forms and strengths

  • 210 mg

Film-coated tablet.

On the market

Generic approvals
No generic approved
Labelers listed (NDC)
2 of which 0 under generic applications, 1 under brand applications, repackagers included

Supply and safety

Pharmacy cost (NADAC)
$6.28 per tablet Ferric citrate 210 mg tablet
Shortage (FDA)
No current entry
Recalls by its makers (FDA)
No recall recorded
FAERS reports
2,194 through July 30, 2026

What is tetraferric tricitrate decahydrate used for?

From the label: indications and usage

Auryxia is a phosphate binder indicated for the control of serum phosphorus levels in adult patients with chronic kidney disease on dialysis. ( 1 ) Auryxia is an iron replacement product indicated for the treatment of iron deficiency anemia in adult patients with chronic kidney disease not on dialysis. ( 1 ) 1.1 Hyperphosphatemia in Chronic Kidney Disease on Dialysis Auryxia is indicated for the control of serum phosphorus levels in adult patients with chronic kidney disease on dialysis. 1.2 Iron Deficiency Anemia in Chronic Kidney Disease Not on Dialysis Auryxia is indicated for the treatment of iron deficiency anemia in adult patients with chronic kidney disease not on dialysis.

Conditions named in the indications of tetraferric tricitrate decahydrate's FDA labels, with every medicine labeled for each:

FDA pharmacologic class: Parenteral Iron Replacement and Phosphate Binder.

Source: FDA drug label (Auryxia), NDA205874 (Keryx Biopharms), as published by Akebia Therapeutics, Inc., effective December 4, 2024 (SPL set aadd18e0-3752-11e4-8510-0800200c9a66), via openFDA; the full label on DailyMed

Is there a generic for tetraferric tricitrate decahydrate (Auryxia)?

No generic tetraferric tricitrate decahydrate is approved (Drugs@FDA, October 8, 2026).

Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)

What do pharmacies pay for tetraferric tricitrate decahydrate (Auryxia)?

In CMS's NADAC survey of October 7, 2026, pharmacies paid $6.28 per Ferric citrate 210 mg tablet, up 6% from $5.89 on October 8, 2025. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.

  • Ferric citrate 210 mg tablet (generic)
  • Auryxia 210 mg tablet (brand)
$7.48
$5.70
January 2024October 2026
NADAC per unit, October 7, 2026
Strength and formBrand or genericPharmacy cost30 tablets, or one pen or vial12-month change
Ferric citrate 210 mg tabletGeneric$6.28 per tablet$188.25+6%
Auryxia 210 mg tabletBrand$7.48 per tablet$224.43+0.9%

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What does the tetraferric tricitrate decahydrate label say about other medicines?

The tetraferric tricitrate decahydrate label names 20 other medicines in its interaction, contraindication or warning sections. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.

Medicine namedSectionWhat the label says
Amlodipinedrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Aspirindrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Atorvastatindrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Calcitrioldrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Ciprofloxacindrug interactionsCiprofloxacin; Take at least 2 hours before or after Auryxia
Clopidogreldrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Digoxindrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Diltiazemdrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Doxercalciferoldrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Doxycyclinedrug interactionsDoxycycline; Take at least 1 hour before Auryxia
Enalaprildrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Fluvastatindrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Glimepiridedrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Levofloxacindrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin

Every other medicine the tetraferric tricitrate decahydrate label names

Medicine namedSectionWhat the label says
Losartandrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; …
Metoprololdrug interactionsAmlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; …
Pravastatindrug interactions… Enalapril Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Propranololdrug interactions… Fluvastatin Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Sitagliptindrug interactions… Glimepiride Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin
Warfarindrug interactions… Levofloxacin Losartan; Metoprolol Pravastatin Propranolol Sitagliptin Warfarin

Check tetraferric tricitrate decahydrate against other medicines

Source: FDA drug label (Auryxia), NDA205874 (Keryx Biopharms), as published by Akebia Therapeutics, Inc., effective December 4, 2024 (SPL set aadd18e0-3752-11e4-8510-0800200c9a66), via openFDA; the full label on DailyMed

What do FAERS reports show for tetraferric tricitrate decahydrate?

The FDA Adverse Event Reporting System holds 2,194 reports that list tetraferric tricitrate decahydrate among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 260 are coded as a death and 420 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.

Reports received each year

The most reported reactions

  • Diarrhoea (named in the label)307
  • Serum Ferritin Increased228
  • Transferrin Saturation Increased169
  • Faeces Discoloured118
  • Death (an outcome recorded in the report)112
  • Constipation (named in the label)83
  • Nausea (named in the label)70
  • Drug Ineffective (a use or a product term, not a reaction)69

Side effects: the label's list and every FAERS reaction

Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026

What else is labeled for the same conditions as tetraferric tricitrate decahydrate?

6 other medicines are given the same way (oral) and in the same FDA class as tetraferric tricitrate decahydrate or labeled mainly for the same use (anemia), the same class first. Anemia lists all 25 medicines labeled for it, by any route. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.

MedicineShared indicationGeneric labelers (oral)Pharmacy costShortage
Ferric citrateAnemia1 labelern/aNo current entry
EltrombopagAnemia13 labelers$25.85 per tablet 50 mg tabletNo current entry
PrednisoloneAnemia23 labelers$0.568 per mL 15 mg/5 mL solutionNo current entry
DaprodustatAnemianone listedn/aNo current entry
MitapivatAnemianone listedn/aNo current entry
VadadustatAnemianone listedn/aNo current entry

Every medicine labeled for the same conditions as tetraferric tricitrate decahydrate

Source: FDA drug labels (indications), NDC Directory, NADAC of October 7, 2026, FDA shortages (October 8, 2026)

What next?

Other parenteral iron replacements
the pharmacologic class, with prices and generics
Tetraferric tricitrate decahydrate side effects
the label's list beside FAERS reports
Check an interaction
what two or more labels say about each other