Prescription medicine
Calcium chloride and potassium chloride and sodium chloride Brand names: Ringers; first approved as Ringer'S
Calcium chloride and potassium chloride and sodium chloride (Ringers) is a prescription medicine with an FDA approval on record since 1971. No generic is listed in FDA's NDC Directory.
- No generic listed
Check it at the source: the calcium chloride and potassium chloride and sodium chloride FDA label on DailyMed (effective August 30, 2023, B. Braun Medical Inc.); the NDA 16693 record on Drugs@FDA; every calcium chloride and potassium chloride and sodium chloride label on DailyMed.
Highlights of the record
FDA label of August 30, 2023; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026
Used for
From the label: indications and usageRinger’s Irrigation USP is indicated for all general irrigation, washing and rinsing purposes which permit use of a sterile, nonpyrogenic electrolyte solution.
Forms and strengths
- 0.86 g/100ml / 0.03 g/100ml / 0.033 g/100ml
- 0.86 g/100ml / 0.033 g/100ml / 0.03 g/100ml
- 30 mg/100ml / 33 mg/100ml / 860 mg/100ml
- 860 mg/100ml / 33 mg/100ml / 30 mg/100ml
Irrigant; injection (solution).
On the market
- Earliest approval on file
- March 22, 1971 Ringer'S In Plastic Container, Baxter Hlthcare; Drugs@FDA’s file, where older or withdrawn approvals can be missing
- Generic approvals
- No generic approved
- Labelers listed (NDC)
- 3 of which 0 under generic applications, 3 under brand applications, repackagers included
Supply and safety
- Pharmacy cost (NADAC)
- Not in the survey
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- No recall recorded
- FAERS reports
- 119 through July 30, 2026
What is calcium chloride and potassium chloride and sodium chloride used for?
From the label: indications and usageRinger’s Irrigation USP is indicated for all general irrigation, washing and rinsing purposes which permit use of a sterile, nonpyrogenic electrolyte solution.
FDA pharmacologic class: Blood Coagulation Factor, Osmotic Laxative, Phosphate Binder and Potassium Salt.
Source: FDA drug label (Ringers), B. Braun Medical Inc., effective August 30, 2023 (SPL set b53c598c-dc7d-4a15-9319-8edf265e7b42), via openFDA; the full label on DailyMed
Is there a generic for calcium chloride and potassium chloride and sodium chloride (Ringers)?
No generic calcium chloride and potassium chloride and sodium chloride is approved (Drugs@FDA, October 8, 2026).
- 1971 earliest approval on file
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What does the calcium chloride and potassium chloride and sodium chloride label say about other medicines?
The calcium chloride and potassium chloride and sodium chloride label names 5 other medicines in its interaction, contraindication or warning sections. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.
| Medicine named | Section | What the label says |
|---|---|---|
| Arginine | drug interactions | These drugs include diuretics and those that cause SIADH (e.g., arginine vasopressin analogs, certain antiepileptic, psychotropic, or cytotoxic drugs). |
| Ceftriaxone | contraindications | CONTRAINDICATIONS Ringer’s Injection is contraindicated in: Neonates (28 days of age or younger) who are receiving concomitant treatment with ceftriaxone, even if separate infusion lines are used, due to the risk of fatal ceftriaxone-calcium salt precipitation in the neonate’s bloodstream [see Warnings and Precautions … |
| Corticotropin | drug interactions | Hypernatremia and Fluid Retention Administration of Ringer’s Injection to patients treated concomitantly with drugs associated with sodium and fluid retention (e.g., corticosteroids or corticotropin) may increase the risk of hypernatremia and volume overload. |
| Digoxin | drug interactions | Consider reducing the volume or rate of Ringer’s Injection due to the increased risk of digoxin toxicity with calcium-containing solutions. |
| Lithium | drug interactions | If concomitant use is unavoidable monitor serum lithium concentrations more frequently. |
Check calcium chloride and potassium chloride and sodium chloride against other medicines
Source: FDA drug label (Ringers), B. Braun Medical Inc., effective August 30, 2023 (SPL set b53c598c-dc7d-4a15-9319-8edf265e7b42), via openFDA; the full label on DailyMed
What do FAERS reports show for calcium chloride and potassium chloride and sodium chloride?
The FDA Adverse Event Reporting System holds 119 reports that list calcium chloride and potassium chloride and sodium chloride among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 20 are coded as a death and 55 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What next?
- Other blood coagulation factors
- the pharmacologic class, with prices and generics
- Calcium chloride and potassium chloride and sodium chloride side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other