Prescription medicine
Calcium chloride, magnesium chloride and 4 other ingredients Brand names: Bss, Balanced; first approved as Isolyte E
Calcium chloride, magnesium chloride and 4 other ingredients (Balanced) is a prescription medicine with an FDA approval on record since 1983. FDA's NDC Directory lists it from 1 generic labeler.
- Generic listed
Check it at the source: the calcium chloride, magnesium chloride and 4 other ingredients FDA label on DailyMed (effective January 25, 2024, Alcon Laboratories, Inc.); the NDA 18899 record on Drugs@FDA; every calcium chloride, magnesium chloride and 4 other ingredients label on DailyMed.
Highlights of the record
FDA label of January 25, 2024; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026
Used for
From the label: indications and usageFor use as an extraocular and intraocular irrigating solution during ocular surgical procedure involving perfusion of the eye with an expected maximum duration of less than 60 minutes.
Forms and strengths
- 6.4 mg/ml / 0.75 mg/ml / 0.48 mg/ml / 0.3 mg/ml / 3.9 mg/ml / 1.7 mg/ml
Solution.
On the market
- Earliest approval on file
- October 31, 1983 Isolyte E In Plastic Container, B Braun; Drugs@FDA’s file, where older or withdrawn approvals can be missing
- Generic approvals
- 2 first September 27, 2006; 1 with a marketed status in Drugs@FDA
- Labelers listed (NDC)
- 2 of which 1 under generic applications, 1 under brand applications, repackagers included
Supply and safety
- Pharmacy cost (NADAC)
- Not in the survey
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- No recall recorded
- FAERS reports
- 1,319 through July 30, 2026
What is calcium chloride, magnesium chloride and 4 other ingredients used for?
From the label: indications and usageFor use as an extraocular and intraocular irrigating solution during ocular surgical procedure involving perfusion of the eye with an expected maximum duration of less than 60 minutes.
FDA pharmacologic class: Blood Coagulation Factor, Calculi Dissolution Agent, Osmotic Laxative, Phosphate Binder and Potassium Salt.
Source: FDA drug label (BSS), Alcon Laboratories, Inc., effective January 25, 2024 (SPL set 4bd4d59c-eb3b-4a5e-9eb7-ae95b0a92bea), via openFDA; the full label on DailyMed
Is there a generic for calcium chloride, magnesium chloride and 4 other ingredients (Balanced)?
The FDA approved the first generic calcium chloride, magnesium chloride and 4 other ingredients on September 27, 2006. 2 generic applications are approved; 1 of them carries a current (not discontinued) marketing status in Drugs@FDA; that status is not evidence that the generic is on sale.
FDA's NDC Directory lists calcium chloride, magnesium chloride and 4 other ingredients from 1 labeler under a generic (ANDA) application and from 1 brand labeler. A listing means the company has registered the product for sale; it does not show that every pharmacy stocks it.
- 1983 earliest approval on file
- 2006 first generic approved
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What do FAERS reports show for calcium chloride, magnesium chloride and 4 other ingredients?
The FDA Adverse Event Reporting System holds 1,319 reports that list calcium chloride, magnesium chloride and 4 other ingredients among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 7 are coded as a death and 118 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Reports received each year
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What next?
- Other blood coagulation factors
- the pharmacologic class, with prices and generics
- Calcium chloride, magnesium chloride and 4 other ingredients side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other