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FDA pharmacologic class

Calculi Dissolution Agent

5 medicines are in FDA's class of calculi dissolution agents: magnesium sulfate, potassium citrate (Urocit-K), trisodium citrate (Tricitrasol), lefamulin (Xenleta) and anhydrous citric acid; 39 combination products also contain one. 10 of the 44 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is epsom salt at $0.0039 per gram (NADAC).

Which medicines are calculi dissolution agent?

Recalls: FDA enforcement reports, 2012 on
MedicineBrand namesGeneric labelers (all forms)Pharmacy costBoxed warningShortageRecalls since 2012
Magnesium sulfatenone listed17 labelers$0.0039 per gram Epsom saltNoNo current entry10
Potassium citrateUrocit-K12 labelers$0.175 per tablet 10 mEq tabletNoNo current entry2
Calcium carbonate and famotidine and magnesium hydroxidePepcid, Dual20 labelers$0.258 per tablet Acid reducer complete tablet chewableNoNo current entry0
Calcium chloride, dextrose, magnesium chloride, sodium chloride and sodium lactateDelflexnone listedn/aNoA presentation being discontinued18
Alanine, arginine and 19 other ingredientsClinimixnone listedn/aNoNo current entry5
Magnesium sulfate and potassium sulfate and sodium sulfateSuprep9 labelers$0.0901 per mL Sod sul-potass sul-mag sul solutionNoNo current entry0
Trisodium citrateTricitrasol2 labelersn/aNoNo current entry0
Magnesium chloride, potassium chloride and 3 other ingredientsNormosol-R, Physiolyte, Isolyte1 labelern/aNoNo current entry0
Calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactateExtranealnone listedn/aNoNo current entry0
Calcium chloride, magnesium chloride and 4 other ingredientsBss, Balanced1 labelern/aNoNo current entry0
Calcium chloride, magnesium chloride, potassium chloride and sodium chloridePlegisol, Cardioplegic2 labelersn/aNoA presentation being discontinued0
Alanine, arginine and 22 other ingredientsPerikabiven, Kabivennone listedn/aNoNo current entry1
Citric acid and lactic acid l- and potassium bitartratePhexxi, Phexxnone listed$6.05 per gram 1.8-1-0.4% vaginal gelNoNo current entry0
Magnesium sulfate and potassium chloride and sodium sulfateSutabnone listed$6.74 per tablet 1.479-0.225-0.188 g tabletNoNo current entry0
Anhydrous citric acid and magnesium oxide and sodium picosulfateClenpiqnone listed$0.518 per mL 175 mL solutionNoNo current entry0
Anhydrous dextrose, calcium chloride and 5 other ingredientsElliottsnone listedn/aNoNo current entry0
Calcium chloride, magnesium chloride and 3 other ingredientsTpnnone listedn/aNoNo current entry0
Citric acid and urea c 13Idkitnone listedn/aNoNo current entry0
Dextrose, magnesium acetate, potassium acetate and sodium chloridenone listednone listedn/aNoNo current entry0
Dextrose, magnesium chloride and 4 other ingredientsnone listednone listedn/aNoNo current entry0
Dextrose, magnesium chloride and 3 other ingredientsnone listednone listedn/aNoNo current entry0
Dextrose, magnesium chloride and 4 other ingredientsnone listednone listedn/aNoNo current entry0
Magnesium chloride, potassium chloride and 5 other ingredientsIsolytenone listedn/aNoNo current entry0
Adenine, anhydrous citric acid, dextrose, sodium phosphate monobasic and trisodium citrateCpda, Teruflexnone listedn/aNoNo current entry0
Alanine, arginine and 18 other ingredientsClinimixnone listedn/aNoNo current entry0
Citric acid, dextrose, sodium citrate and sodium phosphate monobasicPallnone listedn/aNoNo current entry0
Sodium acetate, sodium chloride and 3 other ingredientsIntersol, Solucionnone listedn/aNoNo current entry0
Adenine, citric acid, dextrose, sodium citrate and sodium phosphate monobasicLeukotrapnone listedn/aNoNo current entry0
Anhydrous dextrose, lactic acid and 4 other ingredientsPrismasolnone listedn/aNoNo current entry0
Citric acid and dextrose and sodium citrateAcd3 labelersn/aNoNo current entry0
Adenine, citric acid and 4 other ingredientsAdditivenone listedn/aNoNo current entry0
Anhydrous citric acid and dextrose and sodium citrateAcd-Anone listedn/aNoNo current entry0
Anhydrous citric acid, dextrose, sodium phosphate monobasic and trisodium citratenone listednone listedn/aNoNo current entry0
Anhydrous citric acid and dextrose and trisodium citrateAcdnone listedn/aNoNo current entry0
Anhydrous dextrose, calcium chloride and 5 other ingredientsPrismasolnone listedn/aNoNo current entry0
Citric acid and dextrose and trisodium citrateAcd2 labelersn/aNoNo current entry0
LefamulinXenletanone listedn/aNoNo current entry0
Anhydrous citric acidnone listednone listedn/aNoNo current entry0
Anhydrous citric acid and gluconolactone and magnesium carbonateRenacidinnone listedn/aNoNo current entry0
Anhydrous dextrose, calcium chloride and 4 other ingredientsPrismasolnone listedn/aNoNo current entry0
Calcium chloride, magnesium chloride and 4 other ingredientsPhoxillumnone listedn/aNoNo current entry0
Lactic acid, magnesium chloride, sodium bicarbonate and sodium chloridePrismasolnone listedn/aNoNo current entry0
Magnesium chloride, potassium chloride and 3 other ingredientsPhoxillumnone listedn/aNoNo current entry0
Magnesium sulfate, monobasic and 3 other ingredientsTis-U-Solnone listedn/aNoNo current entry0

Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)

What do pharmacies pay?

Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?