Prescription and over-the-counter medicine
Trisodium citrate Brand names: Tricitrasol
Trisodium citrate (Tricitrasol) is a prescription and over-the-counter medicine. FDA's NDC Directory lists it from 2 generic labelers.
- Generic listed
Check it at the source: the trisodium citrate FDA label on DailyMed (effective April 2, 2024); every trisodium citrate label on DailyMed.
Highlights of the record
FDA label of April 2, 2024; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026
Used for
From the label: indications and usageAnticoagulant Sodium Citrate 4% w/v Solution, USP is intended for use only with automated apheresis devices.
Forms and strengths
- 4 g/100ml
- 14 g/30ml
- 40 mg/ml
Solution; injection (solution).
On the market
- Generic approvals
- No generic approved
- Labelers listed (NDC)
- 5 of which 2 under generic applications, 3 under brand applications, repackagers included; 1 more under the over-the-counter monograph, without an application
Supply and safety
- Pharmacy cost (NADAC)
- Not in the survey
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- No recall recorded
- FAERS reports
- 6,880 through July 30, 2026
What is trisodium citrate used for?
From the label: indications and usageAnticoagulant Sodium Citrate 4% w/v Solution, USP is intended for use only with automated apheresis devices.
Conditions named in the indications of trisodium citrate's FDA labels, with every medicine labeled for each:
From other trisodium citrate labelsAcid reflux and ulcers: Uses For the relief of heartburn, sour stomach, acid indigestion, and upset stomach and accompanying nausea associated with overindulgence in food and drink.
FDA pharmacologic class: Anti-coagulant and Calculi Dissolution Agent.
Source: FDA drug label (ANTICOAGULANT SODIUM CITRATE), Baxter Healthcare Corporation, effective April 2, 2024 (SPL set 7025a0f9-1a56-4416-a3a4-925d755aed90), via openFDA; the full label on DailyMed
Is there a generic for trisodium citrate (Tricitrasol)?
No generic trisodium citrate is approved (Drugs@FDA, October 8, 2026).
FDA's NDC Directory lists trisodium citrate from 2 labelers under a generic (ANDA) application and from 3 brand labelers. A listing means the company has registered the product for sale; it does not show that every pharmacy stocks it.
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What do FAERS reports show for trisodium citrate?
The FDA Adverse Event Reporting System holds 6,880 reports that list trisodium citrate among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 109 are coded as a death and 110 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is. Reports rose sharply in 2022 (4,993, against a median of 13 a year): FAERS counts follow reporting, which news, litigation and label changes can drive, not how often a reaction happens.
Reports received each year
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What else is labeled for the same conditions as trisodium citrate?
21 other medicines are given the same way (oral) and in the same FDA class as trisodium citrate or labeled mainly for the same use (acid reflux and ulcers), the same class first. Acid reflux and ulcers lists all 27 medicines labeled for it, by any route. The first 8 are below. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.
| Medicine | Shared indication | Generic labelers (oral) | Pharmacy cost | Shortage |
|---|---|---|---|---|
| Calcium carbonate and famotidine and magnesium hydroxide | Acid reflux and ulcers | 20 labelers | $0.258 per tablet Acid reducer complete tablet chewable | No current entry |
| Calcium carbonate | Acid reflux and ulcers | none listed | $0.0315 per tablet 750 mg tablet chewable | No current entry |
| Omeprazole | Acid reflux and ulcers | 121 labelers | $0.0295 per capsule 20 mg capsule | A presentation being discontinued |
| Famotidine | Acid reflux and ulcers | 144 labelers | $0.0289 per tablet 20 mg tablet | No current entry |
| Esomeprazole | Acid reflux and ulcers | 117 labelers | $0.145 per capsule 20 mg capsule | No current entry |
| Pantoprazole | Acid reflux and ulcers | 52 labelers | $0.0358 per tablet 40 mg tablet | No current entry |
| Lansoprazole | Acid reflux and ulcers | 59 labelers | $0.106 per capsule 30 mg capsule | No current entry |
| Sucralfate | Acid reflux and ulcers | 43 labelers | $0.173 per tablet 1 g tablet | No current entry |
Every medicine labeled for the same conditions as trisodium citrate
Source: FDA drug labels (indications), NDC Directory, NADAC of October 7, 2026, FDA shortages (October 8, 2026)
What next?
- Alternatives to trisodium citrate
- 21 medicines for the same use
- Other anti-coagulants
- the pharmacologic class, with prices and generics
- Trisodium citrate side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other