Medicines labeled for the same conditions
Alternatives to hydrochlorothiazide and losartan
56 other medicines are given the same way (oral) and in the same FDA class as hydrochlorothiazide and losartan or labeled mainly for the same use (high blood pressure); 12 are in its class, thiazide diuretics: valsartan, olmesartan, irbesartan, telmisartan and 8 more; the others include 9 beta-adrenergic blockers, 9 angiotensin converting enzyme inhibitors and 5 calcium channel blockers (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0805 per olmesartan medoxomil 20 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as hydrochlorothiazide and losartan?
The first 24 of the 56, the same class first. High blood pressure lists all 88 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Hydrochlorothiazide and losartanthiazide diuretic | this medicine | 29 labelers | $0.0762 per tablet 100-12.5 mg tablet | Yes | No current entry |
| Valsartanangiotensin 2 receptor blocker · same class | High blood pressure | 34 labelers | $0.0963 per tablet 40 mg tablet | Yes | A presentation being discontinued |
| Olmesartanangiotensin 2 receptor blocker · same class | High blood pressure | 31 labelers | $0.0805 per tablet 20 mg tablet | Yes | No current entry |
| Irbesartanangiotensin 2 receptor blocker · same class | High blood pressure | 23 labelers | $0.107 per tablet 150 mg tablet | Yes | No current entry |
| Telmisartanangiotensin 2 receptor blocker · same class | High blood pressure | 28 labelers | $0.106 per tablet 20 mg tablet | Yes | No current entry |
| Amlodipine and olmesartancalcium channel blocker · same class | High blood pressure | 14 labelers | $0.248 per unit 10-20 mg | Yes | No current entry |
| Amlodipine and valsartancalcium channel blocker · same class | High blood pressure | 9 labelers | $0.330 per unit 10-160 mg | Yes | No current entry |
| Candesartanangiotensin 2 receptor blocker · same class | High blood pressure | 8 labelers | $0.478 per tablet 16 mg tablet | Yes | No current entry |
| Amlodipine and telmisartancalcium channel blocker · same class | High blood pressure | 3 labelers | $2.88 per unit 40-10 | Yes | No current entry |
| Azilsartanangiotensin 2 receptor blocker · same class | High blood pressure | 1 labeler | $5.47 per tablet 40 mg tablet | Yes | No current entry |
| Amlodipine and indapamide and telmisartanthiazide-like diuretic · same class | High blood pressure | none listed | n/a | Yes | No current entry |
| Azilsartan and chlorthalidonethiazide-like diuretic · same class | High blood pressure | none listed | $8.49 per tablet 40-12.5 mg tablet | Yes | No current entry |
| Chlorothiazidethiazide diuretic · same class | High blood pressure | none listed | n/a | No | A presentation being discontinued |
| Metoprololbeta-adrenergic blocker | High blood pressure | 64 labelers | $0.085 per tablet 100 mg tablet | No | A presentation being discontinued |
| Diltiazemcalcium channel blocker | High blood pressure | 42 labelers | $0.144 per capsule 24h ER(cd) 120 mg capsule | No | A presentation being discontinued |
| Lisinoprilangiotensin converting enzyme inhibitor | High blood pressure | 36 labelers | $0.0254 per tablet 20 mg tablet | Yes | No current entry |
| Propranololbeta-adrenergic blocker | High blood pressure | 38 labelers | $0.0493 per tablet 20 mg tablet | No | In shortage |
| Amlodipinecalcium channel blocker | High blood pressure | 42 labelers | $0.0102 per tablet 5 mg tablet | No | No current entry |
| Clonidinecentral alpha-2 adrenergic agonist | High blood pressure | 37 labelers | $0.0241 per tablet 0.1 mg tablet | No | No current entry |
| Nifedipinedihydropyridine calcium channel blocker | High blood pressure | 32 labelers | $0.130 per tablet 30 mg tablet | No | No current entry |
| Atenololbeta-adrenergic blocker | High blood pressure | 35 labelers | $0.0217 per tablet 25 mg tablet | No | No current entry |
| Labetalolbeta-adrenergic blocker | High blood pressure | 31 labelers | $0.215 per tablet 300 mg tablet | No | No current entry |
| Prazosinalpha-adrenergic blocker | High blood pressure | 33 labelers | $0.0842 per capsule 1 mg capsule | No | A presentation being discontinued |
| Enalaprilangiotensin converting enzyme inhibitor | High blood pressure | 29 labelers | $0.0664 per tablet 10 mg tablet | Yes | No current entry |
| Chlorthalidonethiazide-like diuretic | High blood pressure | 36 labelers | $0.0743 per tablet 25 mg tablet | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Hydrochlorothiazide and losartan: the full record
- label, generics, price, shortages, recalls