azilsartan
Brand names: Edarbi
Edarbyclor is a drug that combines two medicines to lower high blood pressure. It helps reduce the risk of strokes and heart attacks.
Drug Pricing (NADAC)
Brand Price
$7.61/unit
Generic Available
No
AZURITY
Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →
What it does
Edarbyclor is used to treat high blood pressure.
Common side effects
Dizziness, Fatigue
Key warnings
Edarbyclor can harm your unborn baby.
How It Works
Edarbyclor contains two medicines that work in different ways to lower blood pressure. One medicine blocks a substance that tightens blood vessels. The other medicine helps your body get rid of extra salt and water.
How to Take It
Take Edarbyclor once a day. You can take it with or without food. The starting dose is usually one 40/12.5 mg tablet daily. Your doctor may increase the dose to 40/25 mg after 2 to 4 weeks if needed.
Pregnancy & Breastfeeding
Edarbyclor can cause harm to an unborn baby, including injury or death. Do not take this medicine if you are pregnant or plan to become pregnant. It is not recommended to breastfeed while taking Edarbyclor.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule.
Storage
Store Edarbyclor in its original container at room temperature (59°-86°F). Keep the container tightly closed and protect from moisture and light.
Serious Warnings
Edarbyclor can harm your unborn baby. If you are pregnant or become pregnant, stop taking this medicine and tell your doctor right away.
Known Drug Interactions
7.2 Dual Blockade of the Renin-Angiotensin System (RAS) Dual blockade of the RAS with angiotensin receptor blockers, ACE inhibitors, or aliskiren is associated with increased risks of hypotension, hyperkalemia, and changes in renal function (including acute renal failure) compared to monotherapy. Do not coadminister aliskiren with Edarbyclor in patients with diabetes. Avoid use of aliskiren with Edarbyclor in patients with renal impairment (GFR <60 mL/min).
Mechanism: Both drugs block the same system that controls blood pressure, which can cause your blood pressure to drop too low and strain your kidneys. This can also lead to dangerously high potassium levels in your blood.
What to do: Do not take these together if you have diabetes or kidney problems. Your doctor will likely prescribe only one of these to protect your health.
7 DRUG INTERACTIONS Renal clearance of lithium is reduced by diuretics, such as chlorthalidone increasing the risk of lithium toxicity ( 7 ) NSAIDS increase risk of renal dysfunction and interfere with antihypertensive effect ( 7 ) Dual inhibition of the renin-angiotensin system: Increased risk of renal impairment, hypotension, and hyperkalemia ( 7 ) Lithium: Increases in serum lithium concentrations and lithium toxicity ( 7 ) 7.1 Non-Steroidal Anti-Inflammatory Agents including Selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors) In patients who are elderly, volume-depleted (including ...
Mechanism: These drugs work in different ways to lower blood pressure, which can increase the risk of very low blood pressure and kidney problems.
What to do: Your doctor should monitor your blood pressure and kidney function closely while you are taking these medications.
7 DRUG INTERACTIONS Renal clearance of lithium is reduced by diuretics, such as chlorthalidone increasing the risk of lithium toxicity ( 7 ) NSAIDS increase risk of renal dysfunction and interfere with antihypertensive effect ( 7 ) Dual inhibition of the renin-angiotensin system: Increased risk of renal impairment, hypotension, and hyperkalemia ( 7 ) Lithium: Increases in serum lithium concentrations and lithium toxicity ( 7 ) 7.1 Non-Steroidal Anti-Inflammatory Agents including Selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors) In patients who are elderly, volume-depleted (including ...
Mechanism: Azilsartan can make it harder for the kidneys to remove lithium from the body. This causes lithium levels to build up, which can lead to dangerous side effects.
What to do: Your doctor should monitor your lithium blood levels closely. They may need to adjust your lithium dose while you are taking this medication.
Common Questions
What should I do if I feel dizzy after taking Edarbyclor?
Can I take Edarbyclor with other blood pressure medicines?
Can I drink alcohol while taking Edarbyclor?
What if I have kidney problems?
Can Edarbyclor affect my potassium levels?
Is it okay to take NSAIDs like ibuprofen with Edarbyclor?
What if I am taking lithium?
Are there any foods I should avoid?
What does Edarbyclor look like?
Who should not take Edarbyclor?
What are the common side effects of azilsartan?
Does azilsartan interact with other medications?
What drug class is azilsartan?
Is azilsartan safe during pregnancy?
Related Medications in Angiotensin II Receptor Blocker (ARB)
Other drugs grouped near azilsartan — same-class peers and common alternatives.
acebutolol
Sectral
Acebutolol is a medicine that helps lower blood pressure and control irregular heartbeats.
Compare with azilsartan →
aliskiren
Tekturna
Tekturna is a medicine used to treat high blood pressure.
Compare with azilsartan →
amiloride
Midamor
Amiloride is a water pill that helps your body hold onto potassium.
Compare with azilsartan →
amlodipine
Norvasc
Amlodipine (Norvasc) is a drug that lowers blood pressure and treats chest pain.
Compare with azilsartan →
amlodipine/benazepril
Lotrel
Lotrel is a combination medicine that contains amlodipine and benazepril.
Compare with azilsartan →
Medication Guides
Understanding Drug Interactions
How CYP450 enzymes, inhibitors, and inducers affect your medications
Generic vs Brand Name Drugs
FDA requirements, cost savings, and when the difference matters
Narrow Therapeutic Index Drugs
Why some drugs demand precise dosing and monitoring
Common Drug Interactions
Dangerous medication combinations and how to protect yourself
Related Health & Safety Data
🩺 Find a Doctor
Search prescribers for Angiotensin II Receptor Blocker (ARB)
🏨 Hospital Quality
CMS hospital ratings, safety scores & patient outcomes
💊 Supplement Data
NIH DSLD — check supplement ingredients & label claims
🍽️ Food Safety Alerts
FDA recalls, inspections & outbreak investigations
⚠️ Product Recalls
FDA, CPSC & NHTSA recall search
💉 Procedure Costs
Medicare procedure pricing for 9,297 procedures
Save on azilsartan
Compare prices and find discounts at pharmacies near you. Free coupons can save up to 80% on prescriptions.
Disclosure: This link may earn us a commission at no extra cost to you. See our terms.
What the FDA Data Shows for azilsartan
The FDA label for azilsartan (sold under brand names such as Edarbi) classifies it as a prescription-only medication in the Angiotensin II Receptor Blocker (ARB) class. Edarbyclor is used to treat high blood pressure. Official labeling lists 2 commonly reported side effects, including Dizziness, Fatigue.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. Voluntary reports accumulate over the lifetime of a drug and reflect wide-ranging clinical use. The database also lists 3 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated major severity. NADAC pricing from CMS.
Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.
Last updated: July 23, 2025
Read our methodology — how this data is sourced, computed, and verified.
All federal data sources used on this page
- FDA Orange Book — approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed — NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) — post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm — standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files — federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database — current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages