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Medicines labeled for the same conditions

Alternatives to cefoxitin

27 other medicines are given the same way (intravenous) and in the same FDA class as cefoxitin or labeled mainly for the same use (bacterial infections); 10 are in its class, cephalosporin antibacterials: cefazolin, cefepime, ceftriaxone, cefuroxime and 6 more; the others include 2 beta lactamase inhibitors, 2 fluoroquinolone antibacterials and 2 penicillin-class antibacterials (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $1.07 per cefazolin 1 g vial (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as cefoxitin?

The first 24 of the 27, the same class first. Bacterial infections lists all 51 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (intravenous)Pharmacy costBoxed warningShortage
Cefoxitincephalosporin antibacterialthis medicine5 labelersn/aNoNo current entry
Cefazolincephalosporin antibacterial · same classUrinary tract infections7 labelers$1.07 per vial 1 g vialNoNo current entry
Cefepimecephalosporin antibacterial · same classUrinary tract infections8 labelersn/aNoA presentation being discontinued
Ceftriaxonecephalosporin antibacterial · same classBacterial infections, Urinary tract infections7 labelers$1.44 per vial 1 g vialNoNo current entry
Cefuroximecephalosporin antibacterial · same classBacterial infections, Urinary tract infections2 labelersn/aNoNo current entry
Ceftazidimecephalosporin antibacterial · same classBacterial infections3 labelers$3.70 per vial 1 g vialNoA presentation being discontinued
Avibactam and ceftazidimebeta lactamase inhibitor · same classUrinary tract infectionsnone listedn/aNoNo current entry
Cefepime and zidebactamcephalosporin antibacterial · same classUrinary tract infectionsnone listedn/aNoNo current entry
Cefiderocolcephalosporin antibacterial · same classUrinary tract infectionsnone listedn/aNoNo current entry
Cefotaximecephalosporin antibacterial · same classBacterial infections1 labelern/aNoIn shortage
Ceftolozane and tazobactambeta lactamase inhibitor · same classUrinary tract infectionsnone listedn/aNoNo current entry
Vancomycinglycopeptide antibacterialBacterial infections21 labelers$2.31 per vial 500 mg vialNoA presentation being discontinued
Piperacillin and tazobactambeta lactamase inhibitorBacterial infections15 labelers$3.49 per vial 3.375 g vialNoA presentation being discontinued
Levofloxacinfluoroquinolone antibacterialBacterial infections, Urinary tract infections8 labelersn/aYesNo current entry
Clindamycinlincosamide antibacterialBacterial infections6 labelersn/aYesIn shortage
Ampicillinpenicillin-class antibacterialBacterial infections, Urinary tract infections11 labelersn/aNoA presentation being discontinued
Linezolidoxazolidinone antibacterialBacterial infections9 labelersn/aNoNo current entry
Ampicillin and sulbactambeta lactamase inhibitorBacterial infections7 labelersn/aNoNo current entry
Azithromycinmacrolide antimicrobialBacterial infections7 labelersn/aNoA presentation being discontinued
Metronidazolenitroimidazole antimicrobialBacterial infections7 labelersn/aYesIn shortage
Tobramycinaminoglycoside antibacterialBacterial infections, Urinary tract infections7 labelers$0.832 per mL 80 mg/2 mL vialNoA presentation being discontinued
Penicillin gpenicillin-class antibacterialBacterial infections6 labelersn/aNoNo current entry
Tigecyclinetetracycline-class antibacterialBacterial infections4 labelersn/aYesNo current entry
Sulfamethoxazole and trimethoprimsulfonamide antimicrobialBacterial infections, Urinary tract infections2 labelersn/aNoNo current entry
Gentamicinaminoglycoside antibacterialBacterial infections1 labeler$1.30 per mL 80 mg/2 mL vialNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

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