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Medicines labeled for the same conditions

Alternatives to captopril

78 other medicines are given the same way (oral) and in the same FDA class as captopril or labeled mainly for the same use (high blood pressure); 15 are in its class, angiotensin converting enzyme inhibitors: lisinopril, enalapril, hydrochlorothiazide and lisinopril, amlodipine and benazepril and 11 more; the others include 10 thiazide diuretics, 9 beta-adrenergic blockers and 8 calcium channel blockers (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0254 per lisinopril 20 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as captopril?

The first 24 of the 78, the same class first. High blood pressure lists all 88 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Captoprilangiotensin converting enzyme inhibitorthis medicine13 labelers$0.228 per tablet 12.5 mg tabletYesNo current entry
Lisinoprilangiotensin converting enzyme inhibitor · same classHigh blood pressure, Heart failure36 labelers$0.0254 per tablet 20 mg tabletYesNo current entry
Enalaprilangiotensin converting enzyme inhibitor · same classHigh blood pressure, Heart failure29 labelers$0.0664 per tablet 10 mg tabletYesNo current entry
Hydrochlorothiazide and lisinoprilangiotensin converting enzyme inhibitor · same classHigh blood pressure27 labelers$0.0293 per tablet 10-12.5 mg tabletYesNo current entry
Amlodipine and benazeprilcalcium channel blocker · same classHigh blood pressure16 labelers$0.114 per unit 10-20 mgYesNo current entry
Benazeprilangiotensin converting enzyme inhibitor · same classHigh blood pressure21 labelers$0.0789 per tablet 20 mg tabletYesNo current entry
Ramiprilangiotensin converting enzyme inhibitor · same classHigh blood pressure17 labelers$0.0707 per capsule 10 mg capsuleYesNo current entry
Quinaprilangiotensin converting enzyme inhibitor · same classHigh blood pressure, Heart failure9 labelersn/aYesIn shortage
Fosinoprilangiotensin converting enzyme inhibitor · same classHigh blood pressure, Heart failure7 labelers$0.154 per tablet 10 mg tabletYesNo current entry
Benazepril and hydrochlorothiazideangiotensin converting enzyme inhibitor · same classHigh blood pressure3 labelers$0.222 per tablet 20-12.5 mg tabletYesNo current entry
Trandolaprilangiotensin converting enzyme inhibitor · same classHigh blood pressure5 labelers$0.157 per tablet 1 mg tabletYesNo current entry
Hydrochlorothiazide and quinaprilangiotensin converting enzyme inhibitor · same classHigh blood pressure4 labelersn/aYesIn shortage
Enalapril and hydrochlorothiazideangiotensin converting enzyme inhibitor · same classHigh blood pressure2 labelers$0.209 per tablet 10-25 mg tabletYesNo current entry
Fosinopril and hydrochlorothiazideangiotensin converting enzyme inhibitor · same classHigh blood pressure2 labelers$0.634 per tablet 10-12.5 mg tabletYesNo current entry
Trandolapril and verapamilcalcium channel blocker · same classHigh blood pressure1 labelern/aYesNo current entry
Perindoprilangiotensin converting enzyme inhibitor · same classHigh blood pressure1 labeler$0.495 per tablet 4 mg tabletYesNo current entry
Metoprololbeta-adrenergic blockerHigh blood pressure, Heart failure64 labelers$0.085 per tablet 100 mg tabletNoA presentation being discontinued
Diltiazemcalcium channel blockerHigh blood pressure42 labelers$0.144 per capsule 24h ER(cd) 120 mg capsuleNoA presentation being discontinued
Propranololbeta-adrenergic blockerHigh blood pressure38 labelers$0.0493 per tablet 20 mg tabletNoIn shortage
Carvedilolalpha-adrenergic blockerHigh blood pressure, Heart failure41 labelers$0.0179 per tablet 6.25 mg tabletNoNo current entry
Losartanangiotensin 2 receptor blockerHigh blood pressure, Chronic kidney disease44 labelers$0.0327 per tablet 50 mg tabletYesNo current entry
Amlodipinecalcium channel blockerHigh blood pressure42 labelers$0.0102 per tablet 5 mg tabletNoNo current entry
Spironolactonealdosterone antagonistHigh blood pressure, Heart failure38 labelers$0.0426 per tablet 25 mg tabletNoA presentation being discontinued
Hydrochlorothiazidethiazide diureticHigh blood pressure, Heart failure44 labelers$0.0115 per tablet 25 mg tabletNoA presentation being discontinued
Clonidinecentral alpha-2 adrenergic agonistHigh blood pressure37 labelers$0.0241 per tablet 0.1 mg tabletNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

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