Medicines labeled for the same conditions
Alternatives to amiloride and hydrochlorothiazide
14 other medicines are given the same way (oral) and in the same FDA class as amiloride and hydrochlorothiazide or labeled mainly for the same use (heart failure); 2 are in its class, potassium-sparing diuretics: triamterene and chlorothiazide; the others include 2 aldosterone antagonists, 2 loop diuretics and 2 sodium-glucose cotransporter 2 inhibitors (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $5.98 per triamterene 50 mg capsule (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as amiloride and hydrochlorothiazide?
Heart failure lists all 37 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Amiloride and hydrochlorothiazidepotassium-sparing diuretic | this medicine | 1 labeler | $0.450 per tablet 5-50 mg tablet | Yes | No current entry |
| Triamterenepotassium-sparing diuretic · same class | Heart failure | 3 labelers | $5.98 per capsule 50 mg capsule | Yes | No current entry |
| Chlorothiazidethiazide diuretic · same class | Heart failure | none listed | n/a | No | A presentation being discontinued |
| Carvedilolalpha-adrenergic blocker | Heart failure | 41 labelers | $0.0179 per tablet 6.25 mg tablet | No | No current entry |
| Spironolactonealdosterone antagonist | Heart failure | 38 labelers | $0.0426 per tablet 25 mg tablet | No | A presentation being discontinued |
| Furosemideloop diuretic | Heart failure | 33 labelers | $0.026 per tablet 20 mg tablet | No | In shortage |
| Sacubitril and valsartanneprilysin inhibitor | Heart failure | 27 labelers | $0.533 per unit 49-51 mg | Yes | No current entry |
| Bumetanideloop diuretic | Heart failure | 24 labelers | $0.108 per tablet 1 mg tablet | Yes | Resolved |
| Digoxincardiac glycoside | Heart failure | 21 labelers | $0.133 per tablet 125 mcg tablet | No | No current entry |
| Ivabradinehyperpolarization-activated cyclic nucleotide-gated channel blocker | Heart failure | 11 labelers | $0.761 per tablet 5 mg tablet | No | A presentation being discontinued |
| Eplerenonealdosterone antagonist | Heart failure | 9 labelers | $0.308 per tablet 25 mg tablet | No | No current entry |
| Empagliflozinsodium-glucose cotransporter 2 inhibitor | Heart failure | none listed | $11.19 per tablet 10 mg tablet | No | No current entry |
| Hydralazine and isosorbide dinitratearteriolar vasodilator | Heart failure | 3 labelers | $0.714 per tablet 20-37.5 mg tablet | No | No current entry |
| Vericiguatsoluble guanylate cyclase stimulator | Heart failure | none listed | $22.72 per tablet 10 mg tablet | Yes | No current entry |
| Sotagliflozinsodium-glucose cotransporter 2 inhibitor | Heart failure | none listed | $20.37 per tablet 200 mg tablet | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Amiloride and hydrochlorothiazide: the full record
- label, generics, price, shortages, recalls