Empagliflozin Brand names: Jardiance

What is empagliflozin used for?

From the label: indications and usage

JARDIANCE is indicated: to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure. to reduce the risk of sustained decline in eGFR, end-stage kidney disease, cardiovascular death, and hospitalization in adults with chronic kidney disease at risk of progression. to reduce the risk of cardiovascular death in adults with type 2 diabetes mellitus and established cardiovascular disease. as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus. […]

Conditions named in the indications of empagliflozin's FDA labels, with every medicine labeled for each:

• Heart failure
• Type 2 diabetes
• Chronic kidney disease

From other empagliflozin labels

Type 2 diabetes: … at risk of progression. to reduce the risk of cardiovascular death in adults with type 2 diabetes mellitus and established cardiovascular disease. …

FDA pharmacologic class: Sodium-Glucose Cotransporter 2 Inhibitor.

What does the patient leaflet for empagliflozin say first?

The FDA-approved Medication Guide or Patient Information that comes with the medicine, in its own words.

From the patient leaflet: What is the most important information I should know about JARDIANCE?

JARDIANCE can cause serious side effects, including: Diabetic ketoacidosis (increased ketones in your blood or urine) in people with type 1 and other ketoacidosis. JARDIANCE can cause ketoacidosis that can be life-threatening and may lead to death. Ketoacidosis is a serious condition which needs to be treated in a hospital. People with type 1 diabetes have a high risk of getting ketoacidosis. People with type 2 diabetes or pancreas problems also have an increased risk of getting ketoacidosis. Ketoacidosis can also happen in people who: are sick, cannot eat or drink as usual, skip meals, are on a diet high in fat and low in carbohydrates (ketogenic diet), take less than the usual amount of insulin or miss insulin doses, drink too much alcohol, have a loss of too much fluid from the body (volume depletion), or who have surgery. Ketoacidosis can happen even if your blood sugar is less than 250 mg/dL. Your healthcare provider may ask you to periodically check ketones in your urine or blood. Stop taking JARDIANCE and call your healthcare provider or get medical help right away if you get any of the following. If possible, check for ketones in your urine or blood, even if your blood sugar is less than 250 mg/dL: nausea vomiting stomach-area (abdominal) pain tiredness trouble breathing ketones in your urine or blood Dehydration. JARDIANCE can cause some people to become dehydrated (the loss of body water and salt). Dehydration may cause you to feel dizzy, faint, light-headed, or weak, especially when you stand up (orthostatic hypotension). There have been reports of sudden worsening of kidney function in people who are taking JARDIANCE. […]

From the patient leaflet: How should I store JARDIANCE?

Store JARDIANCE at room temperature between 68°F to 77°F (20°C to 25°C). Keep JARDIANCE and all medicines out of the reach of children.

Is there a generic for empagliflozin (Jardiance)?

The FDA approved the first generic empagliflozin on August 3, 2022. 2 generic applications are approved; 1 of them carries a current (not discontinued) marketing status in Drugs@FDA; that status is not evidence that the generic is on sale. Drugs@FDA also holds 8 tentative approvals: the FDA found the generic approvable, but patents or exclusivity keep it from final approval for now.

The Orange Book lists 15 patents for Jardiance tablets: the compound patent runs to August 1, 2028 (pediatric exclusivity to February 1, 2029), and the last listed entry to December 11, 2034. A patent or exclusivity date is not the date a generic goes on sale: court cases and settlements move it either way.

What do pharmacies pay for empagliflozin (Jardiance)?

In CMS's NADAC survey of October 7, 2026, pharmacies paid $11.19 per Jardiance 10 mg tablet, down 44% from $20.13 on October 8, 2025. The survey records the price, not the reason for a change; large moves often follow a new generic or a list-price change. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.

Has empagliflozin been recalled?

The FDA's Enforcement Report lists 2 recalls naming empagliflozin since 2022: 0 Class I (the most serious), 2 Class II, 0 Class III; 0 still ongoing. A recall names products and lots, not every product of the medicine.

What does the empagliflozin label say about other medicines?

The empagliflozin label names 1 other medicine in its interaction, contraindication or warning sections. The labels of 1 other medicine name empagliflozin. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.

Check empagliflozin against other medicines

What do FAERS reports show for empagliflozin?

The FDA Adverse Event Reporting System holds 66,937 reports that list empagliflozin among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 3,360 are coded as a death and 22,129 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.

Reports received each year

• 1,685
• 2,444
• 3,749
• 5,480
• 5,282
• 6,152
• 7,545
• 9,189
• 9,876
• 9,604
• 5,002

• 2016
• 2017
• 2018
• 2019
• 2020
• 2021
• 2022
• 2023
• 2024
• 2025
• 2026

The most reported reactions

• Diabetic Ketoacidosis (named in the label)3,864
• Nausea (named in the label)3,572
• Diarrhoea3,239
• Blood Glucose Increased3,197
• Weight Decreased2,922
• Fatigue2,884
• Off Label Use (a use or a product term, not a reaction)2,787
• Vomiting (named in the label)2,693

Side effects: the label's list and every FAERS reaction

What else is labeled for the same conditions as empagliflozin?

22 other medicines are given the same way (oral) and in the same FDA class as empagliflozin or labeled mainly for the same use (heart failure), the same class first. Heart failure lists all 37 medicines labeled for it, by any route. The first 8 are below. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.

Every medicine labeled for the same conditions as empagliflozin

How does empagliflozin compare with medicines for the same use?

5 side-by-side pages set empagliflozin beside a medicine whose label shares a use: approvals, generics, pharmacy cost, warnings and supply.

• Dapagliflozin
• Glimepiride
• Metformin
• Pioglitazone
• Sitagliptin

What next?

Alternatives to empagliflozin

22 medicines for the same use

Other SGLT2 inhibitors

the pharmacologic class, with prices and generics

Empagliflozin side effects

the label's list beside FAERS reports

Check an interaction

what two or more labels say about each other