Zinc Sulfate and Moxifloxacin Interaction
Drug interaction information between Zinc Sulfate and Moxifloxacin.
Zinc Sulfate and Moxifloxacin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Zinc Sulfate and Moxifloxacin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Zinc binds to the antibiotic in your digestive tract, preventing the drug from reaching the rest of your body to treat infection.
FDA Label Information
Oral administration of moxifloxacin hydrochloride with antacids containing aluminum or magnesium, with sucralfate, with metal cations such as iron, or with multivitamins containing iron or zinc, or with formulations containing divalent and trivalent cations such as didanosine buffered tablets for oral suspension or the pediatric powder for oral solution, may substantially interfere with the absorption of moxifloxacin hydrochloride, resulting in systemic concentrations considerably lower than desired.
Zinc Sulfate Also Interacts With
- Baloxavir Marboxil moderate
- Delafloxacin minor
- Levofloxacin minor
- Tetracycline minor
Moxifloxacin Also Interacts With
- Lefamulin moderate
- Warfarin minor
- Sotalol minor
- Sucralfate minor
- Clozapine minor
Frequently Asked Questions
What SPL severity band is on file for Zinc Sulfate + Moxifloxacin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Moxifloxacin has 10 labeled pairs on file vs Zinc Sulfate's 5. In the minor band specifically: Zinc Sulfate has 4 (also Delafloxacin, Levofloxacin, Tetracycline); Moxifloxacin has 9 (also Warfarin, Sotalol, Sucralfate, Clozapine).
What mechanism field is on file for Zinc Sulfate and Moxifloxacin?
Zinc binds to the antibiotic in your digestive tract, preventing the drug from reaching the rest of your body to treat infection.
Moxifloxacin's labeled portfolio outnumbers Zinc Sulfate
SPL source-record counts only. This page's band is minor · classes on file: Zinc Sulfate (Mineral Supplement); Moxifloxacin (Fluoroquinolone Antibiotic).
0 major · 1 moderate · 4 minor · 5 total
- Other minor peers for Zinc Sulfate
- Delafloxacin
- Levofloxacin
- Tetracycline
0 major · 1 moderate · 9 minor · 10 total
- Other minor peers for Moxifloxacin
- Warfarin
- Sotalol
- Sucralfate
- Clozapine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.