Zinc Sulfate and Delafloxacin Interaction

Drug interaction information between Zinc Sulfate and Delafloxacin.

Zinc Sulfate and Delafloxacin have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Zinc Sulfate and Delafloxacin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Zinc Sulfate

Mineral Supplement

Drug B

Delafloxacin

Fluoroquinolone Antibiotic

How They Interact

Zinc binds to the antibiotic in your stomach, which stops the body from absorbing it properly. This can make the antibiotic much less effective at fighting your infection.

FDA Label Information

Oral administration of BAXDELA with antacids containing aluminum or magnesium, with sucralfate, with metal cations such as iron, or with multivitamins containing iron or zinc, or with formulations containing divalent and trivalent cations such as didanosine buffered tablets for oral suspension or the pediatric powder for oral solution, may substantially interfere with the absorption of BAXDELA, resulting in systemic concentrations considerably lower than desired.

Delafloxacin Also Interacts With

View all Delafloxacin interactions →

Frequently Asked Questions

What SPL severity band is on file for Zinc Sulfate + Delafloxacin?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Zinc Sulfate has 5 labeled pairs on file vs Delafloxacin's 2. In the minor band specifically: Zinc Sulfate has 4 (also Levofloxacin, Moxifloxacin, Tetracycline); Delafloxacin has 2 (also Sucralfate).

What mechanism field is on file for Zinc Sulfate and Delafloxacin?

Zinc binds to the antibiotic in your stomach, which stops the body from absorbing it properly. This can make the antibiotic much less effective at fighting your infection.

Zinc Sulfate's labeled portfolio outnumbers Delafloxacin

SPL source-record counts only. This page's band is minor · classes on file: Zinc Sulfate (Mineral Supplement); Delafloxacin (Fluoroquinolone Antibiotic).

Zinc Sulfate

0 major · 1 moderate · 4 minor · 5 total

Delafloxacin

0 major · 0 moderate · 2 minor · 2 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.