Solifenacin and Mirabegron Interaction
Drug interaction information between Solifenacin and Mirabegron.
Solifenacin and Mirabegron have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Solifenacin and Mirabegron. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Taking these two bladder medicines together can slightly change how your body absorbs or handles each drug.
FDA Label Information
Drug interaction studies were conducted in adult patients to investigate the effect of coadministered drugs on the pharmacokinetics of mirabegron and the effect of mirabegron on the pharmacokinetics of coadministered drugs (e.g., ketoconazole, rifampin, solifenacin succinate, tamsulosin, and oral contraceptives) [see Clinical Pharmacology ( 12.3 )] .
Solifenacin Also Interacts With
- Darunavir major
- Itraconazole major
- Ketoconazole minor
Mirabegron Also Interacts With
- Tamsulosin minor
- Warfarin minor
- Ketoconazole minor
- Rifampin minor
- Digoxin minor
Frequently Asked Questions
What SPL severity band is on file for Solifenacin + Mirabegron?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Mirabegron has 6 labeled pairs on file vs Solifenacin's 4. In the minor band specifically: Solifenacin has 2 (also Ketoconazole); Mirabegron has 6 (also Tamsulosin, Warfarin, Ketoconazole, Rifampin).
What mechanism field is on file for Solifenacin and Mirabegron?
Taking these two bladder medicines together can slightly change how your body absorbs or handles each drug.
Solifenacin carries more major-labeled pairs than Mirabegron
SPL source-record counts only. This page's band is minor · classes on file: Solifenacin (Anticholinergic (Overactive Bladder)); Mirabegron (Beta-3 Agonist (Overactive Bladder)).
Solifenacin has 2 major-labeled pairs vs Mirabegron's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 6 minor · 6 total
- Other minor peers for Mirabegron
- Tamsulosin
- Warfarin
- Ketoconazole
- Rifampin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.