What the FDA labels say about taking them together
Citalopram and warfarin
Citalopram's FDA label of October 9, 2023 names warfarin in its drug interactions section, and warfarin's label names citalopram too. The citalopram label: “Concomitant use of CELEXA and an antiplatelet or anticoagulant may potentiate the risk of bleeding.”
Check it at the source: the citalopram FDA label on DailyMed (effective October 9, 2023, Allergan, Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).
What does the citalopram label say about warfarin?
Citalopram label, drug interactionsClinical Impact: Concomitant use of CELEXA and an antiplatelet or anticoagulant may potentiate the risk of bleeding. Intervention: Inform patients of the increased risk of bleeding associated with the concomitant use of CELEXA and antiplatelet agents and anticoagulants. For patients taking warfarin, carefully monitor the international normalized ratio [ see Warning and Precautions ( 5.4 )]. …
Citalopram label, warnings and precautionsIn cr eased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, other antiplatelet drugs, warfarin and other anticoagulants may increase this risk ( 5.4 ).
Source: FDA drug label (Citalopram, NDA215428), Almatica Pharma LLC, effective October 7, 2025 (SPL set 2f815b0c-6da7-cb61-e89c-7de628092d0d), via openFDA
Source: FDA drug label (Celexa), NDA020822 (Abbvie), as published by Allergan, Inc., effective October 9, 2023 (SPL set 4259d9b1-de34-43a4-85a8-41dd214e9177), via openFDA; the full label on DailyMed
What does the warfarin label say about citalopram?
Warfarin label, drug interactionsDrug Class: Serotonin Reuptake Inhibitors; Specific Drugs: citalopram, desvenlafaxine, duloxetine, escitalopram, fluoxetine, fluvoxamine, milnacipran, paroxetine, sertraline, venlafaxine, vilazodone
Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Citalopram | Warfarin | |
|---|---|---|
| Labeled for | Depression | Blood clots (DVT and PE), Atrial fibrillation |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.026 per tablet 10 mg tablet | $0.093 per tablet 2 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once