What the FDA labels say about taking them together
Cyclosporine and isavuconazonium
Isavuconazonium's FDA label of April 25, 2025 names cyclosporine in its drug interactions section; the cyclosporine labels PlainMeds reads (4) do not name isavuconazonium. The isavuconazonium label: “Cyclosporine Use with Caution Concomitant administration of CRESEMBA and cyclosporine results in increase in cyclosporine exposure.”
Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the isavuconazonium FDA label on DailyMed (effective April 25, 2025, Astellas Pharma US, Inc.).
What does the cyclosporine label say about isavuconazonium?
Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name isavuconazonium in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
What does the isavuconazonium label say about cyclosporine?
Isavuconazonium label, drug interactionsCyclosporine Use with Caution Concomitant administration of CRESEMBA and cyclosporine results in increase in cyclosporine exposure.
Source: FDA drug label (CRESEMBA), Astellas Pharma US, Inc., effective April 25, 2025 (SPL set 8f7f73b8-586a-4df0-935f-fecd4696c16c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cyclosporine | Isavuconazonium | |
|---|---|---|
| Labeled for | Organ transplant rejection, Rheumatoid arthritis | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $1.04 per unit 0.05% eye emulsion | $114.00 per capsule 186 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once