What the FDA labels say about taking them together
Bupropion and isavuconazonium
Isavuconazonium's FDA label of April 25, 2025 names bupropion in its drug interactions section; the bupropion labels PlainMeds reads (4) do not name isavuconazonium. The isavuconazonium label: “Bupropion Use with Caution Concomitant administration of CRESEMBA and bupropion results in decrease in bupropion exposure.”
Check it at the source: the bupropion FDA label on DailyMed (effective June 21, 2024); the isavuconazonium FDA label on DailyMed (effective April 25, 2025, Astellas Pharma US, Inc.).
What does the bupropion label say about isavuconazonium?
Bupropion's label (effective June 21, 2024) and its 3 other brand-application labels do not name isavuconazonium in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (BUPROPION HYDROCHLORIDE), Epic Pharma LLC, effective June 21, 2024 (SPL set 9fb44e96-6160-4a4a-90cb-91764c0dcd89), via openFDA; the full label on DailyMed
What does the isavuconazonium label say about bupropion?
Isavuconazonium label, drug interactionsBupropion Use with Caution Concomitant administration of CRESEMBA and bupropion results in decrease in bupropion exposure.
Source: FDA drug label (CRESEMBA), Astellas Pharma US, Inc., effective April 25, 2025 (SPL set 8f7f73b8-586a-4df0-935f-fecd4696c16c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Bupropion | Isavuconazonium | |
|---|---|---|
| Labeled for | Depression, Quitting smoking | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0785 per tablet 150 mg tablet | $114.00 per capsule 186 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once