Glyburide and Eprosartan Interaction

Drug interaction information between Glyburide and Eprosartan.

Glyburide and Eprosartan have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Glyburide and Eprosartan. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Glyburide

Sulfonylurea

Drug B

Eprosartan

Angiotensin II Receptor Blocker (ARB)

How They Interact

Eprosartan does not change how glyburide works to control your blood sugar levels.

FDA Label Information

Concomitant administration of eprosartan and glyburide in diabetic patients did not affect 24-hour plasma glucose profiles. Eprosartan has been shown to have no effect on the pharmacokinetics of digoxin and the pharmacodynamics of warfarin and glyburide.

Frequently Asked Questions

What SPL severity band is on file for Glyburide + Eprosartan?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

How many labeled pairs sit in each drug's minor band?

Glyburide and Eprosartan tie at 9 labeled pairs each. minor-band counts: Glyburide 8 alongside Colesevelam, Etodolac, Fluconazole, Miglitol; Eprosartan 8 alongside Hydrochlorothiazide, Warfarin, Nifedipine, Ketoconazole.

What mechanism field is on file for Glyburide and Eprosartan?

Eprosartan does not change how glyburide works to control your blood sugar levels.

Eprosartan carries more major-labeled pairs than Glyburide

SPL source-record counts only. This page's band is minor · classes on file: Glyburide (Sulfonylurea); Eprosartan (Angiotensin II Receptor Blocker (ARB)).

Eprosartan has 1 major-labeled pair vs Glyburide's 0. This page itself is in the minor band, not the major band.

Glyburide

0 major · 1 moderate · 8 minor · 9 total

Eprosartan

1 major · 0 moderate · 8 minor · 9 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.