PlainMeds provides educational information only. This is not medical advice. Always consult your doctor or pharmacist.

eprosartan vs glyburide

Side-by-side comparison of eprosartan and glyburide. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Concomitant administration of eprosartan and glyburide in diabetic patients did not affect 24-hour plasma glucose profiles. Eprosartan has been shown to have no effect on the pharmacokinetics of digoxin and the pharmacodynamics of warfarin and glyburide.

Recommendation: It is safe to take these together, but continue to check your blood sugar levels as your doctor recommends.

Drug Class
eprosartan Angiotensin II Receptor Blocker (ARB)
glyburide Sulfonylurea
Type
eprosartan Prescription
glyburide Prescription
Summary
eprosartan

Eprosartan (Teveten) is a medicine that lowers high blood pressure. It can be used alone or with other blood pressure medicines.

glyburide

Glyburide is a medicine that helps lower blood sugar in adults with type 2 diabetes. It works along with diet and exercise.

What It Treats
eprosartan

Eprosartan is used to treat high blood pressure (hypertension). It can be used by itself or with other medicines to lower your blood pressure. Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems.

glyburide

Glyburide is used to help control blood sugar levels in adults who have type 2 diabetes. It is prescribed in addition to diet and exercise. This medicine helps your body use insulin better, which lowers your blood sugar.

How It Works
eprosartan

Eprosartan belongs to a class of drugs called angiotensin II receptor blockers (ARBs). It works by blocking a substance in your body that tightens blood vessels. This helps blood vessels relax, which lowers blood pressure.

glyburide

Glyburide belongs to a class of drugs called sulfonylureas. It works by helping your pancreas release more insulin. Insulin then helps move sugar from your blood into your cells for energy.

Common Side Effects
eprosartan
  • Viral infection
  • Injury
  • Fatigue
  • Abdominal pain
  • Joint pain
glyburide
  • Nausea
  • Heartburn
  • Fullness in your upper abdomen
FAERS Reports
eprosartan

No adverse event reports.

glyburide
  • High blood sugar 3,038
  • Feeling sick to your stomach 2,020
  • Weight loss 1,536
  • Loose stools 1,282
  • Feeling lightheaded 1,201
Serious Warnings
eprosartan

If you become pregnant, stop taking eprosartan right away. This medicine can cause serious harm or death to your unborn baby.

glyburide

Oral diabetes medicines like glyburide may increase your risk of heart problems, compared to treatment with diet alone or diet plus insulin. Talk to your doctor about the risks and benefits of taking glyburide.

Pregnancy
eprosartan

Eprosartan can harm your unborn baby, even causing death. Stop taking this medicine as soon as you know you are pregnant. It is not known if eprosartan passes into breast milk, so talk to your doctor about the best way to feed your baby if you are taking this medicine.

glyburide

Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if glyburide will harm your unborn baby. Talk to your doctor if you are breastfeeding.

Also Compare, Nearby Drugs

How to Read This eprosartan vs glyburide Comparison

eprosartan is classified in the Angiotensin II Receptor Blocker (ARB) drug class, while glyburide sits within the Sulfonylurea class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, eprosartan has 0 submissions while glyburide has 9,077. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to eprosartan does not change how glyburide works to control your blood sugar levels.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between eprosartan and glyburide - always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.