Glyburide and Etodolac Interaction

Drug interaction information between Glyburide and Etodolac.

Glyburide and Etodolac have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Glyburide and Etodolac. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Glyburide

Sulfonylurea

Drug B

Etodolac

Nonsteroidal Anti-Inflammatory Drug (NSAID)

How They Interact

These two drugs do not seem to affect how the body processes or removes each other. There is no known interaction between them based on current studies.

FDA Label Information

Glyburide Etodolac has no apparent pharmacokinetic interaction when administered with glyburide.

Frequently Asked Questions

What SPL severity band is on file for Glyburide + Etodolac?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Etodolac has 10 labeled pairs on file vs Glyburide's 9. In the minor band specifically: Glyburide has 8 (also Colesevelam, Eprosartan, Fluconazole, Miglitol); Etodolac has 9 (also Hydrochlorothiazide, Furosemide, Aspirin, Methotrexate).

What mechanism field is on file for Glyburide and Etodolac?

These two drugs do not seem to affect how the body processes or removes each other. There is no known interaction between them based on current studies.

Etodolac's labeled portfolio outnumbers Glyburide

SPL source-record counts only. This page's band is minor · classes on file: Glyburide (Sulfonylurea); Etodolac (Nonsteroidal Anti-Inflammatory Drug (NSAID)).

Glyburide

0 major · 1 moderate · 8 minor · 9 total

Etodolac

0 major · 1 moderate · 9 minor · 10 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.