dutasteride vs furosemide
Side-by-side comparison of dutasteride and furosemide. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
major Known Drug Interaction
7.5 Furosemide Tamsulosin Tamsulosin had no effect on the pharmacodynamics (excretion of electrolytes) of furosemide. While furosemide produced an 11% to 12% reduction in tamsulosin hydrochloride C max and AUC, these changes are expected to be clinically insignificant and do not require adjustment of the dose of tamsulosin [see Clinical Pharmacology ( 12.3 ) ] .
Recommendation: You do not need to change your dose when taking these medications together.
Avodart
Lasix
Dutasteride and tamsulosin hydrochloride capsules contain two medicines to treat enlarged prostate in men. They help improve symptoms like frequent urination.
Furosemide is a water pill (diuretic). It helps your body get rid of extra water and salt.
This medicine treats benign prostatic hyperplasia (BPH), also known as enlarged prostate, in men. It helps with symptoms like needing to urinate often, especially at night. It is for men who have an enlarged prostate causing these problems. This medicine is not approved to prevent prostate cancer.
This medicine treats swelling (edema) from heart failure, liver problems, or kidney disease. It can also treat high blood pressure. Furosemide is helpful when you need a stronger diuretic.
Dutasteride lowers a hormone called dihydrotestosterone (DHT) that causes the prostate to grow. Tamsulosin relaxes the muscles in the prostate and bladder. This combination helps urine flow more easily.
Furosemide works in your kidneys. It helps your kidneys remove more salt and water from your blood. This lowers the amount of fluid in your body and lowers blood pressure.
- • Problems with ejaculation
- • Impotence (trouble getting or keeping an erection)
- • Decreased sex drive
- • Dizziness
- • Breast enlargement or tenderness
- • Dizziness
- • Headache
- • Blurred vision
- • Nausea
- • Vomiting
- Difficulty breathing 1,233
- Tiredness 1,142
- Feeling lightheaded or unsteady 986
- Weakness 933
- Loose stools 897
- Difficulty breathing 29,099
- Tiredness 20,389
- Diarrhea 19,940
- Feeling sick to your stomach 18,682
- Sudden kidney damage 18,530
This medicine can cause dizziness or fainting, so be careful to avoid falls or injuries. Do not take this medicine with other alpha-blockers, as this can lower your blood pressure too much. This medicine can affect PSA levels, which are used to screen for prostate cancer. Tell your doctor you are taking this medicine before any PSA tests. This medicine may increase the risk of high-grade prostate cancer. Pregnant women should not handle this medicine.
Furosemide can cause you to lose too much fluid and electrolytes. This can lead to dehydration, low blood pressure, and kidney problems. Your doctor should check your blood regularly while you are taking this medicine.
This medicine is not for use in women. It can cause birth defects in a male fetus if a pregnant woman is exposed to it. Pregnant women or women who may become pregnant should not handle these capsules.
Tell your doctor if you are pregnant or plan to become pregnant. Furosemide may not be safe during pregnancy. Talk to your doctor about the risks and benefits of taking this medicine while breastfeeding.
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How to Read This dutasteride vs furosemide Comparison
dutasteride is classified in the 5-Alpha Reductase Inhibitor drug class, while furosemide sits within the Loop Diuretic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, dutasteride has 5,191 submissions while furosemide has 106,640. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known major interaction flagged in FDA labeling, attributed to furosemide slightly lowers the amount of the other drug in your blood, but the effect is too small to matter.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between dutasteride and furosemide - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.