cyclosporine vs furosemide
Side-by-side comparison of cyclosporine and furosemide. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
moderate Known Drug Interaction
Concomitant use of cyclosporine and furosemide is associated with increased risk of gouty arthritis secondary to furosemide-induced hyperurecemia and cyclosporine impairment of renal urate excretion.
Recommendation: Your doctor should monitor your uric acid levels and watch for signs of joint pain. Dosage adjustments may be necessary if gout symptoms develop.
Neoral, Sandimmune, Restasis
Lasix
Vevye eye drops contain cyclosporine. They help treat the signs and symptoms of dry eye disease.
Furosemide is a water pill (diuretic). It helps your body get rid of extra water and salt.
Vevye treats the signs and symptoms of dry eye disease. Dry eye can cause discomfort, stinging, and blurred vision. This medicine can help reduce these symptoms.
This medicine treats swelling (edema) from heart failure, liver problems, or kidney disease. It can also treat high blood pressure. Furosemide is helpful when you need a stronger diuretic.
Vevye contains cyclosporine, which is an immunosuppressant. It works by decreasing inflammation in the eyes. This helps your eyes make more tears.
Furosemide works in your kidneys. It helps your kidneys remove more salt and water from your blood. This lowers the amount of fluid in your body and lowers blood pressure.
- • Irritation where the drops are applied (8%)
- • Dizziness
- • Headache
- • Blurred vision
- • Nausea
- • Vomiting
- Eye feels irritated 7,786
- Fever 4,066
- Eye ache 3,808
- Feeling sick to your stomach 3,623
- Loose stools 3,562
- Difficulty breathing 29,099
- Tiredness 20,389
- Diarrhea 19,940
- Feeling sick to your stomach 18,682
- Sudden kidney damage 18,530
To avoid eye injury or contamination, do not touch the bottle tip to your eye or any other surface. Do not use Vevye while wearing contact lenses. If you wear contacts, remove them before using the drops. You can put them back in 15 minutes after using Vevye.
Furosemide can cause you to lose too much fluid and electrolytes. This can lead to dehydration, low blood pressure, and kidney problems. Your doctor should check your blood regularly while you are taking this medicine.
It is not known if Vevye will harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Cyclosporine can pass into breast milk after being taken orally, but it is unknown if it passes into breast milk from eye drops. Talk to your doctor if you are breastfeeding.
Tell your doctor if you are pregnant or plan to become pregnant. Furosemide may not be safe during pregnancy. Talk to your doctor about the risks and benefits of taking this medicine while breastfeeding.
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How to Read This cyclosporine vs furosemide Comparison
cyclosporine is classified in the Calcineurin Inhibitor (Immunosuppressant) drug class, while furosemide sits within the Loop Diuretic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, cyclosporine has 22,845 submissions while furosemide has 106,640. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to furosemide raises uric acid levels in the blood, while cyclosporine makes it harder for the kidneys to remove it. this combination can cause uric acid to build up and lead to painful gouty arthritis.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between cyclosporine and furosemide - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.