Felbamate and Drospirenone Interaction
Drug interaction information between Felbamate and Drospirenone.
Felbamate and Drospirenone have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Felbamate and Drospirenone. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Felbamate can cause your body to process birth control hormones faster, which makes the pill less effective at preventing pregnancy.
FDA Label Information
Some drugs or herbal products that may decrease the effectiveness of hormonal contraceptives include phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampin, topiramate and products containing St.
Felbamate Also Interacts With
- Clonazepam major
- Erythromycin minor
- Phenobarbital minor
- Carbamazepine minor
- Estradiol minor
Drospirenone Also Interacts With
- Estradiol major
- Atorvastatin minor
- Omeprazole minor
- Lamotrigine minor
- Topiramate minor
Frequently Asked Questions
What SPL severity band is on file for Felbamate + Drospirenone/Ethinyl Estradiol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Drospirenone has 30 labeled pairs on file vs Felbamate's 16. In the minor band specifically: Felbamate has 15 (also Erythromycin, Phenobarbital, Carbamazepine, Estradiol); Drospirenone has 29 (also Atorvastatin, Omeprazole, Lamotrigine, Topiramate).
What mechanism field is on file for Felbamate and Drospirenone/Ethinyl Estradiol?
Felbamate can cause your body to process birth control hormones faster, which makes the pill less effective at preventing pregnancy.
Drospirenone's labeled portfolio outnumbers Felbamate
SPL source-record counts only. This page's band is minor · classes on file: Felbamate (Anticonvulsant); Drospirenone (Combined Oral Contraceptive).
1 major · 0 moderate · 15 minor · 16 total
- Other minor peers for Felbamate
- Erythromycin
- Phenobarbital
- Carbamazepine
- Estradiol
1 major · 0 moderate · 29 minor · 30 total
- Other minor peers for Drospirenone
- Atorvastatin
- Omeprazole
- Lamotrigine
- Topiramate
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.