Dutasteride and Furosemide Interaction
Drug interaction information between Dutasteride and Furosemide.
Dutasteride and Furosemide have a documented major interaction in FDA labeling.
FDA drug labeling documents a major-severity interaction between Dutasteride and Furosemide. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Furosemide slightly lowers the amount of the other drug in your blood, but the effect is too small to matter.
FDA Label Information
7.5 Furosemide Tamsulosin Tamsulosin had no effect on the pharmacodynamics (excretion of electrolytes) of furosemide. While furosemide produced an 11% to 12% reduction in tamsulosin hydrochloride C max and AUC, these changes are expected to be clinically insignificant and do not require adjustment of the dose of tamsulosin [see Clinical Pharmacology ( 12.3 ) ] .
Dutasteride Also Interacts With
- Tamsulosin moderate
- Warfarin moderate
- Paroxetine minor
- Atenolol minor
- Diltiazem minor
Furosemide Also Interacts With
- Dutasteride/Tamsulosin major
- Tamsulosin major
- Cyclosporine moderate
- Lithium moderate
- Oxaprozin moderate
Frequently Asked Questions
What SPL severity band is on file for Dutasteride + Furosemide?
Compiled FDA labeling labels this pair major. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Furosemide has 36 labeled pairs on file vs Dutasteride's 16. In the major band specifically: Dutasteride has 1; Furosemide has 3 (also Dutasteride/Tamsulosin, Tamsulosin).
What mechanism field is on file for Dutasteride and Furosemide?
Furosemide slightly lowers the amount of the other drug in your blood, but the effect is too small to matter.
Furosemide carries more major-labeled pairs than Dutasteride
SPL source-record counts only. This page's band is major · classes on file: Dutasteride (5-Alpha Reductase Inhibitor); Furosemide (Loop Diuretic).
Furosemide has 3 major-labeled pairs vs Dutasteride's 1.
1 major · 2 moderate · 13 minor · 16 total
Dutasteride has no other major-band peer in this dataset besides Furosemide.
3 major · 4 moderate · 29 minor · 36 total
- Other major peers for Furosemide
- Dutasteride/Tamsulosin
- Tamsulosin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.