What the FDA labels say about taking them together
Benazepril and lithium
Benazepril's FDA label of September 30, 2025 names lithium in its drug interactions section; the lithium labels PlainMeds reads (4) do not name benazepril. The benazepril label: “Increased risk of renal impairment, hypotension and hyperkalemia Lithium: Symptoms of lithium toxicity Neprilysin Inhibitor:”
Check it at the source: the benazepril FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC); the lithium FDA label on DailyMed (effective December 23, 2025, Glenmark Pharmaceuticals Inc., USA).
What does the benazepril label say about lithium?
Benazepril label, drug interactionsIncreased risk of renal impairment, hypotension and hyperkalemia ( 7.4 ) Lithium: Symptoms of lithium toxicity ( 7.6 ) Neprilysin Inhibitor:
Source: FDA drug label (Lotensin), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2abb091b-a53e-46b0-9b84-e5ee8f2bdd8e), via openFDA; the full label on DailyMed
What does the lithium label say about benazepril?
Lithium's label (effective December 23, 2025) and its 3 other brand-application labels do not name benazepril in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lithium Carbonate), Glenmark Pharmaceuticals Inc., USA, effective December 23, 2025 (SPL set 63b3790f-a9b5-47f4-bae1-ddf8b43c13c1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Benazepril | Lithium | |
|---|---|---|
| Labeled for | High blood pressure | Bipolar disorder |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.0789 per tablet 20 mg tablet | $0.104 per capsule 300 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once