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anidulafungin vs cyclosporine

Side-by-side comparison of anidulafungin and cyclosporine. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

7 DRUG INTERACTIONS 7.1 Cyclosporine Administration of multiple doses of anidulafungin and cyclosporine to healthy subjects resulted in no significant alteration in the steady state pharmacokinetics of either drug. No dosage adjustment of cyclosporine or anidulafungin is needed when the two drugs are co-administered [see Clinical Pharmacology (12.3) ] .

Recommendation: No dose changes are needed when taking these two medications at the same time.

Drug Class
anidulafungin Echinocandin Antifungal
cyclosporine Calcineurin Inhibitor (Immunosuppressant)
Type
anidulafungin Prescription
cyclosporine Prescription
Summary
anidulafungin

Eraxis is an antifungal medicine. It treats certain Candida infections in your body.

cyclosporine

Vevye eye drops contain cyclosporine. They help treat the signs and symptoms of dry eye disease.

What It Treats
anidulafungin

Eraxis treats candidemia and other Candida infections, like intra-abdominal abscesses and peritonitis. It can be used in adults and children 1 month and older. Eraxis also treats esophageal candidiasis (a Candida infection in the esophagus) in adults. However, Eraxis may not work as well for esophageal candidiasis, and the infection may come back.

cyclosporine

Vevye treats the signs and symptoms of dry eye disease. Dry eye can cause discomfort, stinging, and blurred vision. This medicine can help reduce these symptoms.

How It Works
anidulafungin

Eraxis belongs to a class of drugs called echinocandins. It works by stopping the growth of the fungus Candida. It does this by blocking a key part of the fungal cell wall.

cyclosporine

Vevye contains cyclosporine, which is an immunosuppressant. It works by decreasing inflammation in the eyes. This helps your eyes make more tears.

Common Side Effects
anidulafungin
  • Low potassium levels
  • Nausea
  • Diarrhea
  • Vomiting
  • Fever
cyclosporine
  • Irritation where the drops are applied (8%)
FAERS Reports
anidulafungin
  • Many organs stop working right 171
  • Dangerous drop in blood pressure due to infection 127
  • Blood infection 115
  • Lung infection 94
  • Fever 90
cyclosporine
  • Eye feels irritated 7,786
  • Fever 4,066
  • Eye ache 3,808
  • Feeling sick to your stomach 3,623
  • Loose stools 3,562
Serious Warnings
anidulafungin

Eraxis can cause liver problems. Your doctor should check your liver function while you are taking Eraxis. Allergic reactions, including shock, can happen. Tell your doctor right away if you have any signs of an allergic reaction, like rash, hives, flushing, itching, trouble breathing, or low blood pressure. Eraxis contains fructose. If you have hereditary fructose intolerance, you should not take Eraxis.

cyclosporine

To avoid eye injury or contamination, do not touch the bottle tip to your eye or any other surface. Do not use Vevye while wearing contact lenses. If you wear contacts, remove them before using the drops. You can put them back in 15 minutes after using Vevye.

Pregnancy
anidulafungin

Eraxis may harm your unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Eraxis passes into breast milk. Talk to your doctor about the risks and benefits of breastfeeding while taking Eraxis.

cyclosporine

It is not known if Vevye will harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Cyclosporine can pass into breast milk after being taken orally, but it is unknown if it passes into breast milk from eye drops. Talk to your doctor if you are breastfeeding.

Also Compare, Nearby Drugs

How to Read This anidulafungin vs cyclosporine Comparison

anidulafungin is classified in the Echinocandin Antifungal drug class, while cyclosporine sits within the Calcineurin Inhibitor (Immunosuppressant) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, anidulafungin has 597 submissions while cyclosporine has 22,845. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to these two drugs do not change how the body processes or breaks down each other. they can be used together without affecting the amount of medicine in your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between anidulafungin and cyclosporine - always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.