What the FDA labels say about taking them together
Albuterol and digoxin
Albuterol's FDA label of April 30, 2026 names digoxin in its drug interactions section, and digoxin's label names albuterol too. The albuterol label: “Consider monitoring potassium levels. Digoxin: May decrease serum digoxin levels.”
Check it at the source: the albuterol FDA label on DailyMed (effective April 30, 2026, Ritedose Pharmaceuticals, LLC); the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.).
What does the albuterol label say about digoxin?
Albuterol label, drug interactionsMean decreases of 16% to 22% in serum digoxin levels were demonstrated after single dose intravenous and oral administration of albuterol, respectively, to normal volunteers who had received digoxin for 10 days.
Albuterol Sulfate Hfa label (NuCare Pharmaceuticals,Inc., June 18, 2024), drug interactionsConsider monitoring potassium levels. ( 7.2 ) Digoxin: May decrease serum digoxin levels.
Source: FDA drug label (Albuterol Sulfate Hfa, NDA021457), NuCare Pharmaceuticals,Inc., effective June 18, 2024 (SPL set 8c278b6f-d32b-b750-e053-2995a90ad7e9), via openFDA
Source: FDA drug label (Albuterol Sulfate, NDA020503), Preferred Pharmaceuticals Inc., effective January 14, 2026 (SPL set d6acb5a7-555a-463a-ae65-2911d6789b42), via openFDA
Source: FDA drug label (Albuterol Sulfate Inhalation Solution), Ritedose Pharmaceuticals, LLC, effective April 30, 2026 (SPL set d4c532be-1f41-60d3-e053-2995a90a98be), via openFDA; the full label on DailyMed
What does the digoxin label say about albuterol?
Digoxin label, drug interactionsAcarbose, activated charcoal, albuterol, antacids, certain cancer chemotherapy or radiation therapy, cholestyramine, colestipol, extenatide, kaolin-pectin, meals high in bran, metoclopramide, miglitol, neomycin, penicillamine, phenytoin, rifampin, St. John’s Wort, sucralfate, sulfasalazine; Measure serum digoxin concentrations before initiating concomitant drugs. Continue monitoring and increase digoxin dose by approximately 20-40% as necessary.
Source: FDA drug label (Digoxin, NDA021648), Hikma Pharmaceuticals USA Inc., effective April 10, 2025 (SPL set 1b7e5c6e-e052-41b0-a4ce-05dfe62faaaf), via openFDA
Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Albuterol | Digoxin | |
|---|---|---|
| Labeled for | Asthma | Heart failure, Atrial fibrillation |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.288 per tablet 2 mg tablet | $0.133 per tablet 125 mcg tablet |
| Shortage now | Resolved | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once