Albuterol and Albuterol/Ipratropium Interaction
Drug interaction information between Albuterol and Albuterol/Ipratropium.
Albuterol and Albuterol/Ipratropium have a documented moderate interaction in FDA labeling.
FDA drug labeling documents a moderate-severity interaction between Albuterol and Albuterol/Ipratropium. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Both of these products contain the same type of medicine. Taking them together can cause you to get too much of the drug, which can lead to a racing heart or jitters.
FDA Label Information
Avoid coadministration of COMBIVENT RESPIMAT and other sympathomimetic agents (7.2) Beta-blockers: Inhibit the effect of albuterol. (7.4) Monoamine oxidase inhibitors (MAOs) or tricyclic antidepressants: May potentiate effect of albuterol on the vascular system. 7.3 Beta-receptor Blocking Agents Beta-receptor blocking agents and albuterol inhibit the effect of each other.
Albuterol Also Interacts With
- Theophylline major
- Atomoxetine moderate
- Digoxin minor
- Glimepiride minor
- Insulin Aspart minor
Frequently Asked Questions
What SPL severity band is on file for Albuterol + Albuterol/Ipratropium?
Compiled FDA labeling labels this pair moderate. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Albuterol has 16 labeled pairs on file vs Albuterol/Ipratropium's 1. In the moderate band specifically: Albuterol has 2 (also Atomoxetine); Albuterol/Ipratropium has 1.
What mechanism field is on file for Albuterol and Albuterol/Ipratropium?
Both of these products contain the same type of medicine. Taking them together can cause you to get too much of the drug, which can lead to a racing heart or jitters.
Albuterol carries more major-labeled pairs than Albuterol/Ipratropium
SPL source-record counts only. This page's band is moderate · classes on file: Albuterol (Short-Acting Beta-2 Agonist); Albuterol/Ipratropium (Beta-2 Agonist / Anticholinergic Combination).
Albuterol has 1 major-labeled pair vs Albuterol/Ipratropium's 0. This page itself is in the moderate band, not the major band.
0 major · 1 moderate · 0 minor · 1 total
Albuterol/Ipratropium has no other moderate-band peer in this dataset besides Albuterol.
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.