Albuterol and Insulin Aspart Interaction

Drug interaction information between Albuterol and Insulin Aspart.

Albuterol and Insulin Aspart have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Albuterol and Insulin Aspart. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Albuterol

Short-Acting Beta-2 Agonist

Drug B

Insulin Aspart

Rapid-Acting Insulin

How They Interact

Albuterol can make insulin less effective at lowering your blood sugar. This means your blood sugar levels might stay higher than they should while using this medication.

FDA Label Information

Drugs That May Decrease the Blood Glucose Lowering Effect of NOVOLOG Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. • Drugs that may decrease the blood glucose lowering effect: atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral...

Insulin Aspart Also Interacts With

View all Insulin Aspart interactions →

Frequently Asked Questions

What SPL severity band is on file for Albuterol + Insulin Aspart?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Albuterol has 16 labeled pairs on file vs Insulin Aspart's 11. In the minor band specifically: Albuterol has 13 (also Digoxin, Glimepiride, Insulin Degludec, Insulin Detemir); Insulin Aspart has 8 (also Clonidine, Olanzapine, Lithium, Clozapine).

What mechanism field is on file for Albuterol and Insulin Aspart?

Albuterol can make insulin less effective at lowering your blood sugar. This means your blood sugar levels might stay higher than they should while using this medication.

Albuterol carries more major-labeled pairs than Insulin Aspart

SPL source-record counts only. This page's band is minor · classes on file: Albuterol (Short-Acting Beta-2 Agonist); Insulin Aspart (Rapid-Acting Insulin).

Albuterol has 1 major-labeled pair vs Insulin Aspart's 0. This page itself is in the minor band, not the major band.

Albuterol

1 major · 2 moderate · 13 minor · 16 total

Insulin Aspart

0 major · 3 moderate · 8 minor · 11 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.