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What the label lists and what reports show

Chloroprocaine side effects

Chloroprocaine's FDA label lists its adverse reactions in its own words. FAERS holds 138 reports naming it through July 30, 2026; the reaction reported most often, leaving out the conditions it is used for, product-use terms and outcomes, is eye pain (19 reports).

  • Generic listed

Check it at the source: the chloroprocaine FDA label on DailyMed (effective September 1, 2022, Fresenius Kabi USA, LLC); the FDA FAERS public dashboard.

What does the label list?

From the label: adverse reactions

Systemic: The most commonly encountered acute adverse experiences that demand immediate countermeasures are related to the central nervous system and the cardiovascular system. These adverse experiences are generally dose related and may result from rapid absorption from the injection site, diminished tolerance, or from unintentional intravascular injection of the local anesthetic solution. In addition to systemic dose-related toxicity, unintentional subarachnoid injection of drug during the intended performance of caudal or lumbar epidural block or nerve blocks near the vertebral column (especially in the head and neck region) may result in underventilation or apnea (“Total Spinal”). Factors influencing plasma protein binding, such as acidosis, systemic diseases that alter protein production, or competition of other drugs for protein binding sites, may diminish individual tolerance. …

Source: FDA drug label, Fresenius Kabi USA, LLC, effective September 1, 2022 (SPL set a844e68a-1462-40e4-be5e-f56214906eb9), via openFDA; the full label on DailyMed

What do FAERS reports show?

138 reports list chloroprocaine among the medicines taken, each a report of something that happened, not proof the medicine caused it; 0 are coded as a death and 9 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is. Of the 20 reactions below, 3 are named by the same term (in US spelling) in the label's adverse reactions, warnings or patient leaflet; a reaction the label does not name may still be there under another word, and a report does not show that the medicine caused it.

The 25 most reported reactions

  • Drug Ineffective (a use or a product term, not a reaction)62
  • Underdose (a use or a product term, not a reaction)54
  • Eye Pain19
  • Eye Irritation18
  • Ocular Hyperaemia8
  • Lacrimation Increased7
  • Ocular Discomfort7
  • Off Label Use (a use or a product term, not a reaction)7
  • Product Temperature Excursion Issue7
  • Conjunctival Hyperaemia6
  • Hypersensitivity3
  • Hypotension (named in the label)3
  • Product Label Confusion3
  • Vision Blurred3
  • Anaesthetic Complication2
  • Areflexia2
  • Arthralgia2
  • Back Pain2
  • Bradycardia (named in the label)2
  • Corneal Abrasion2
  • Drug Dose Omission (a use or a product term, not a reaction)2
  • Dyspnoea2
  • Headache (named in the label)2
  • Hypoaesthesia2
  • Intentional Product Use Issue (a use or a product term, not a reaction)2

Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; reactions as MedDRA preferred terms

What next?

Chloroprocaine: the full record
label, generics, price, shortages, recalls
Side effects hub
the most reported medicines and reactions