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Medicines labeled for the same conditions

Alternatives to piperacillin and tazobactam

20 other medicines are given the same way (intravenous) and in the same FDA class as piperacillin and tazobactam or labeled mainly for the same use (bacterial infections); 3 are in its class, beta lactamase inhibitors: ampicillin, ampicillin and sulbactam and penicillin g; the others include 4 cephalosporin antibacterials, 2 fluoroquinolone antibacterials and 2 aminoglycoside antibacterials (FDA labels read October 8, 2026).

Which medicines are labeled for the same conditions as piperacillin and tazobactam?

Bacterial infections lists all 51 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (intravenous)Pharmacy costBoxed warningShortage
Piperacillin and tazobactambeta lactamase inhibitorthis medicine15 labelers$3.49 per vial 3.375 g vialNoA presentation being discontinued
Ampicillinpenicillin-class antibacterial · same classBacterial infections11 labelersn/aNoA presentation being discontinued
Ampicillin and sulbactambeta lactamase inhibitor · same classBacterial infections7 labelersn/aNoNo current entry
Penicillin gpenicillin-class antibacterial · same classBacterial infections6 labelersn/aNoNo current entry
Vancomycinglycopeptide antibacterialBacterial infections21 labelers$2.31 per vial 500 mg vialNoA presentation being discontinued
Levofloxacinfluoroquinolone antibacterialBacterial infections8 labelersn/aYesNo current entry
Clindamycinlincosamide antibacterialBacterial infections6 labelersn/aYesIn shortage
Linezolidoxazolidinone antibacterialBacterial infections9 labelersn/aNoNo current entry
Cefoxitincephalosporin antibacterialBacterial infections5 labelersn/aNoNo current entry
Azithromycinmacrolide antimicrobialBacterial infections7 labelersn/aNoA presentation being discontinued
Metronidazolenitroimidazole antimicrobialBacterial infections7 labelersn/aYesIn shortage
Tobramycinaminoglycoside antibacterialBacterial infections7 labelers$0.832 per mL 80 mg/2 mL vialNoA presentation being discontinued
Cefuroximecephalosporin antibacterialBacterial infections2 labelersn/aNoNo current entry
Tigecyclinetetracycline-class antibacterialBacterial infections4 labelersn/aYesNo current entry
Ceftazidimecephalosporin antibacterialBacterial infections3 labelers$3.70 per vial 1 g vialNoA presentation being discontinued
Sulfamethoxazole and trimethoprimsulfonamide antimicrobialBacterial infections2 labelersn/aNoNo current entry
Gentamicinaminoglycoside antibacterialBacterial infections1 labeler$1.30 per mL 80 mg/2 mL vialNoNo current entry
Cilastatin and imipenemrenal dehydropeptidase inhibitorBacterial infections2 labelersn/aNoA presentation being discontinued
ErythromycinmacrolideBacterial infections3 labelersn/aNoNo current entry
Moxifloxacinfluoroquinolone antibacterialBacterial infections1 labelern/aYesA presentation being discontinued
Cefotaximecephalosporin antibacterialBacterial infections1 labelern/aNoIn shortage

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Piperacillin and tazobactam: the full record
label, generics, price, shortages, recalls