Medicines labeled for the same conditions
Alternatives to insulin degludec
13 other medicines are given the same way (subcutaneous) and in the same FDA class as insulin degludec or labeled mainly for the same use (type 2 diabetes); 6 are in its class, insulin analogs: insulin glargine, insulin aspart, insulin lispro, insulin detemir and 2 more; the others include 4 GLP-1 receptor agonists, 1 glucose-dependent insulinotropic polypeptide receptor agonist and 1 insulin (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $2.90 per mL (Insulin glargine-yfgn u100 pen) (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as insulin degludec?
Type 2 diabetes lists all 52 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (subcutaneous) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Insulin degludecinsulin analog | this medicine | none listed | $11.39 per mL 100 unit/mL pen | No | No current entry |
| Insulin glargineinsulin analog · same class | Type 2 diabetes, Type 1 diabetes | none listed | $2.90 per mL 100 pen | No | A presentation being discontinued |
| Insulin aspartinsulin analog · same class | Type 2 diabetes, Type 1 diabetes | none listed | $6.95 per mL 100 unit/mL vial | No | No current entry |
| Insulin lisproinsulin analog · same class | Type 2 diabetes, Type 1 diabetes | none listed | $10.19 per mL 100 unit/mL kwikpen | No | A presentation being discontinued |
| Insulin detemirinsulin analog · same class | Type 2 diabetes, Type 1 diabetes | none listed | n/a | No | No current entry |
| Insulin glulisineinsulin analog · same class | Type 2 diabetes, Type 1 diabetes | none listed | $8.16 per mL 100 unit/mL vial | No | No current entry |
| Insulin glargine and lixisenatideGLP-1 receptor agonist · same class | Type 2 diabetes | none listed | $57.06 per mL 100 unit-33 mcg/mL pen | No | No current entry |
| Tirzepatideglucose-dependent insulinotropic polypeptide receptor agonist | Type 2 diabetes | none listed | $538.68 per mL 10 mg/0.5 mL pen | Yes | No current entry |
| LiraglutideGLP-1 receptor agonist | Type 2 diabetes | 9 labelers | $31.41 per mL 2-pak 18 mg/3 mL | Yes | In shortage |
| SemaglutideGLP-1 receptor agonist | Type 2 diabetes | none listed | $331.99 per mL 0.25-0.5 mg/dose (2 mg/3 mL) pen | Yes | A presentation being discontinued |
| Insulin humaninsulin | Type 2 diabetes, Type 1 diabetes | none listed | $4.26 per mL 70-30 vial | No | No current entry |
| DulaglutideGLP-1 receptor agonist | Type 2 diabetes | none listed | $487.57 per mL 0.75 mg/0.5 mL pen | Yes | No current entry |
| ExenatideGLP-1 receptor agonist | Type 2 diabetes | 1 labeler | $300.17 per mL 10 mcg dose pen injection | No | No current entry |
| Pramlintideamylin analog | Type 2 diabetes, Type 1 diabetes | none listed | n/a | Yes | A presentation being discontinued |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Insulin degludec: the full record
- label, generics, price, shortages, recalls
- Insulin degludec vs insulin glargine
- two records side by side